ID R1GMB7_BOTPV Unreviewed; 753 AA.
AC R1GMB7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Putative ubiquitin-protein ligase e3a protein {ECO:0000313|EMBL:EOD47139.1};
GN ORFNames=UCRNP2_6112 {ECO:0000313|EMBL:EOD47139.1};
OS Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus)
OS (Neofusicoccum parvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Neofusicoccum.
OX NCBI_TaxID=1287680 {ECO:0000313|EMBL:EOD47139.1, ECO:0000313|Proteomes:UP000013521};
RN [1] {ECO:0000313|Proteomes:UP000013521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-NP2 {ECO:0000313|Proteomes:UP000013521};
RX PubMed=23766404; DOI=10.1128/genomea.00339-13;
RA Blanco-Ulate B., Rolshausen P., Cantu D.;
RT "Draft genome sequence of Neofusicoccum parvum isolate UCR-NP2, a fungal
RT vascular pathogen associated with grapevine cankers.";
RL Genome Announc. 1:E0033913-E0033913(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
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DR EMBL; KB916359; EOD47139.1; -; Genomic_DNA.
DR RefSeq; XP_007585380.1; XM_007585318.1.
DR AlphaFoldDB; R1GMB7; -.
DR STRING; 1287680.R1GMB7; -.
DR KEGG; npa:UCRNP2_6112; -.
DR eggNOG; KOG0941; Eukaryota.
DR HOGENOM; CLU_369600_0_0_1; -.
DR OMA; ININMDA; -.
DR OrthoDB; 1820836at2759; -.
DR Proteomes; UP000013521; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 2.
DR InterPro; IPR015158; Bud22_dom.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF09073; BUD22; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Ligase {ECO:0000313|EMBL:EOD47139.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013521};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 1..293
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 274..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 360..392
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 274..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..518
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 83064 MW; 465F92E860317415 CRC64;
MGKLEGEQGV DQGGVAQEFF RVALAEAFNP DNGMFTVDSQ TRMTWFQPFS LEPLSRFELI
GLLFSIAVYN GITLPSVRII SEKGGQTFRG YEFSFEARGL IININMDAMN EDAEIPSPHT
LLDYTDGLEI SPSSSNPTPI VNWPPGPEAP LVTNTNREQF VRDYVSWLTD KSIRPQFEAF
ARGFRTCLPA QHLALLRPSL LSHIVEGSTD IDTRALERVA RYDGGFDAAH PFVRIFWDSV
HAMPQEQKRK LLEFVTASDR VPVAGIESVV FWHASSNSSP PRPSTTRSSY LPTRERADPH
GHATAAATTT MPKRKRSDDS EQPAASDRAT AKQRKHLPPR LEQGKKALNK ALRVSRGFER
QKLSRRRKAA EKEGKAKEVE RIDAEIEALK KVEYHVLAET HLYKTLLKIK SVAEHPALPP
WVKVPEGKGK GDAAAMNVQA RLFNANPTKE AMGEVVRDVR AILGLEDGGK GPKAKKAKGG
EEKAGKAKAR VATPESSEES SDEESMDDGE EGEWDSEEFE GFSERIAASS DEESEEDIKA
ALKRNYKPVR DLSFTPPSSR EASPSLSPEP TFSDDSVSES SESAPKSKSK AKGPVITNKS
TFLPSLSAVG YISGSESEAE DLDEDIAPPK KNRRGQRARQ QLWEKKYGKE AKHLGKQKEK
EKNDRNAGWD AKRGAVDGAG GRGKGRFGRS DRGENRGGRG PKATDANLVE LGKKKDHRDD
AGKLHPSWEA AKKAKEKAKL GNVQFQGKKV VFD
//
