ID R1IAQ3_9PSEU Unreviewed; 781 AA.
AC R1IAQ3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Probable phosphoketolase {ECO:0000256|HAMAP-Rule:MF_01403};
DE EC=4.1.2.- {ECO:0000256|HAMAP-Rule:MF_01403};
GN ORFNames=H480_05334 {ECO:0000313|EMBL:EOD69606.1};
OS Amycolatopsis vancoresmycina DSM 44592.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD69606.1, ECO:0000313|Proteomes:UP000014139};
RN [1] {ECO:0000313|EMBL:EOD69606.1, ECO:0000313|Proteomes:UP000014139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD69606.1,
RC ECO:0000313|Proteomes:UP000014139};
RA Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964,
CC ECO:0000256|HAMAP-Rule:MF_01403};
CC -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623,
CC ECO:0000256|HAMAP-Rule:MF_01403}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOD69606.1}.
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DR EMBL; AOUO01000054; EOD69606.1; -; Genomic_DNA.
DR RefSeq; WP_003061237.1; NZ_AOUO01000054.1.
DR AlphaFoldDB; R1IAQ3; -.
DR PATRIC; fig|1292037.4.peg.1043; -.
DR eggNOG; COG3957; Bacteria.
DR OrthoDB; 9768449at2; -.
DR Proteomes; UP000014139; Unassembled WGS sequence.
DR GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02011; TPP_PK; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR HAMAP; MF_01403; Phosphoketolase; 1.
DR InterPro; IPR023962; Phosphoketolase.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR Pfam; PF03894; XFP; 1.
DR Pfam; PF09363; XFP_C; 1.
DR Pfam; PF09364; XFP_N; 1.
DR PIRSF; PIRSF017245; Phosphoketolase; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_01403};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052, ECO:0000256|HAMAP-
KW Rule:MF_01403}.
FT DOMAIN 15..361
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09364"
FT DOMAIN 578..779
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09363"
SQ SEQUENCE 781 AA; 86366 MW; 9B5A940BCFA9F88B CRC64;
MTALDARPAV LGRPELAQVD ALWRAANYLS AGQIYLMANP LLREQLRPEH VKPRLLGHWG
TSPGLNFVYA HLNRAILAHD LNAMLVTGPG HGGPALLANT WLEGSYTEAW PEVTRDAAGM
AELFRQFSFP GGVPSHVAPQ VPGSIHEGGE LGYSLAHAFG AAFDNPGLLV ACVVGDGEAE
TGPLATSWHA NKFLDPARDG AVLPILHLNG YKIANPTVLS RIPPAELDAL LRGYGYSPIY
VEGSDPQSMH QAMAAALDSA IATLAERRGV WPMIVLRSPK GWTGPSVVDG KPVEGTWRAH
QVPLAEVRTN PDHLKQLEDW LRSYRPAELF DESGRPVADV TAMIPAGDRR MGANPHANGG
ILLRPLTLPD TSAHAVAVSA PGVTVAEPTR VLGRFLRDVF ALNADRANFR LFGPDETASN
RLDAVYDVTA KEWQAAIEPV DEHLARDGRV LEVLSEHLCQ GWLEGYLLSG RHGLFSCYEA
FVHIVDSMVN QHIKWLRVHR QIPWRRPVAS LNYLLTSHVW RQDHNGFSHQ DPGFVDHVAN
KSAEVVRVYF PPDTNTLLEV AAHCLRSRDY VNVVVAGKND TPNWLDAEQA ALHCARGVSI
WEWASTHTDR EPDVVLACAG DAPTLEVMAA AKILRQELPS LAVRVVNVVD LMRLQPESEH
PHGLSDRGYD ALFTPDRPVI FAYHGYPWLI HRLAYRRTGH HELHVRGYTE HGTTTTPFDM
LVLNHLDRFQ LVIDVLDRIP GLAATAGVLR QRMTEAQGRH RRYIRTHGED LPEVRNWTWE
G
//
