ID R2LY04_ENTFC Unreviewed; 410 AA.
AC R2LY04;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Cell division protein DivIB {ECO:0000256|HAMAP-Rule:MF_00912};
GN Name=divIB {ECO:0000256|HAMAP-Rule:MF_00912};
GN ORFNames=UA3_02724 {ECO:0000313|EMBL:EOH52142.1};
OS Enterococcus faecium EnGen0263.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158553 {ECO:0000313|EMBL:EOH52142.1, ECO:0000313|Proteomes:UP000013667};
RN [1] {ECO:0000313|EMBL:EOH52142.1, ECO:0000313|Proteomes:UP000013667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAA1280 {ECO:0000313|EMBL:EOH52142.1,
RC ECO:0000313|Proteomes:UP000013667};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Courvalin P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus faecium UAA1280.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Cell division protein that may be involved in stabilizing or
CC promoting the assembly of the division complex. {ECO:0000256|HAMAP-
CC Rule:MF_00912}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00912};
CC Single-pass type II membrane protein {ECO:0000256|HAMAP-Rule:MF_00912}.
CC Note=Localizes to the division septum. {ECO:0000256|HAMAP-
CC Rule:MF_00912}.
CC -!- SIMILARITY: Belongs to the FtsQ/DivIB family. DivIB subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_00912}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH52142.1}.
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DR EMBL; AJAD01000032; EOH52142.1; -; Genomic_DNA.
DR RefSeq; WP_010733374.1; NZ_KB946089.1.
DR AlphaFoldDB; R2LY04; -.
DR PATRIC; fig|1158553.3.peg.2734; -.
DR HOGENOM; CLU_046278_0_0_9; -.
DR Proteomes; UP000013667; Unassembled WGS sequence.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.10960; -; 1.
DR HAMAP; MF_00912; DivIB; 1.
DR InterPro; IPR005548; Cell_div_FtsQ/DivIB_C.
DR InterPro; IPR026580; DivIB.
DR InterPro; IPR034746; POTRA.
DR InterPro; IPR013685; POTRA_FtsQ_type.
DR PANTHER; PTHR37820; CELL DIVISION PROTEIN DIVIB; 1.
DR PANTHER; PTHR37820:SF1; CELL DIVISION PROTEIN FTSQ; 1.
DR Pfam; PF03799; FtsQ_DivIB_C; 1.
DR Pfam; PF08478; POTRA_1; 1.
DR PROSITE; PS51779; POTRA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_00912};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_00912};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_00912};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00912};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00912};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00912}.
FT TRANSMEM 117..135
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00912"
FT DOMAIN 139..210
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 46245 MW; E3BC89D5ABF3295C CRC64;
MSKKKEPKKL SHSSSDENNL TPWQKANRKY LAEQGMKNQE PKIEDTPLDT PLSDSEEERT
VQEEQQETSQ SESQSEKKIE FFEEIKQKKN GGPYNGSFLN RLPNLKSQRH KVLFRRLALI
ITVLGIPLIF LIYYVSPYSK LQAVAVSGNK VVNSQEIISD TKLSLGENVW GQYFDRSTYI
ERLKKAQPRI EKAAIHFKGI NEFDLDVTEY KEIALIAKDN QYYPVIENGT VLDEKVANPT
KNLPILEEFK DSAKIKELTK QYNQLSSELQ KAISEIKYTP RASNKNLIQL NMNDGNQVIV
NINNLANQMK YYSQVAKDMD EKGVIDMEVG IYSYPYSSTQ ETAESDQAEE TTGSEENADQ
TNGSSEEAET QAADTPESSD TNGSSDSNNS SEASQIEDNP STTPSSLNEN
//
