ID R2PC60_ENTFC Unreviewed; 207 AA.
AC R2PC60;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Resolvase/invertase-type recombinase catalytic domain-containing protein {ECO:0000259|PROSITE:PS51736};
GN ORFNames=UA3_02422 {ECO:0000313|EMBL:EOH53786.1};
OS Enterococcus faecium EnGen0263.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158553 {ECO:0000313|EMBL:EOH53786.1, ECO:0000313|Proteomes:UP000013667};
RN [1] {ECO:0000313|EMBL:EOH53786.1, ECO:0000313|Proteomes:UP000013667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAA1280 {ECO:0000313|EMBL:EOH53786.1,
RC ECO:0000313|Proteomes:UP000013667};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Courvalin P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus faecium UAA1280.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC {ECO:0000256|ARBA:ARBA00009913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH53786.1}.
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DR EMBL; AJAD01000023; EOH53786.1; -; Genomic_DNA.
DR RefSeq; WP_002288897.1; NZ_KB946113.1.
DR AlphaFoldDB; R2PC60; -.
DR PATRIC; fig|1158553.3.peg.2434; -.
DR HOGENOM; CLU_010686_8_3_9; -.
DR Proteomes; UP000013667; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR CDD; cd03768; SR_ResInv; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.1390; Resolvase, N-terminal catalytic domain; 1.
DR InterPro; IPR006118; Recombinase_CS.
DR InterPro; IPR006119; Resolv_N.
DR InterPro; IPR036162; Resolvase-like_N_sf.
DR InterPro; IPR006120; Resolvase_HTH_dom.
DR PANTHER; PTHR30461; DNA-INVERTASE FROM LAMBDOID PROPHAGE; 1.
DR PANTHER; PTHR30461:SF2; RESOLVASE HOMOLOG YNEB; 1.
DR Pfam; PF02796; HTH_7; 1.
DR Pfam; PF00239; Resolvase; 1.
DR SMART; SM00857; Resolvase; 1.
DR SUPFAM; SSF53041; Resolvase-like; 1.
DR PROSITE; PS00397; RECOMBINASES_1; 1.
DR PROSITE; PS51736; RECOMBINASES_3; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 1..150
FT /note="Resolvase/invertase-type recombinase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51736"
FT ACT_SITE 9
FT /note="O-(5'-phospho-DNA)-serine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606118-50,
FT ECO:0000256|PROSITE-ProRule:PRU10137"
SQ SEQUENCE 207 AA; 23807 MW; 2BACA4D313871839 CRC64;
MYLAYLRVSS DDQSLARQHK LIENWSVKNN IAEDDLKIFE EKVSGKNIEN RPELQELISF
IRERDTIIIP SLDRLARNSK DTKDLLQLFR SKGASIEILD LPSFNGVTDP ALRDLLTNLV
IEVFSYVAEN ERKKIKERQK QGIEIAKKNG RYTGKKIQYH ANATGKNKLI YDEIVDGLKK
KETISKIAKN AGVTRKTVYR VKRDLGM
//
