ID R2Q625_9ENTE Unreviewed; 345 AA.
AC R2Q625;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=LacI family sugar-binding transcriptional regulator {ECO:0000313|EMBL:EOH90738.1};
GN ORFNames=UAS_00469 {ECO:0000313|EMBL:EOH90738.1};
OS Enterococcus asini ATCC 700915.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158606 {ECO:0000313|EMBL:EOH90738.1, ECO:0000313|Proteomes:UP000013777};
RN [1] {ECO:0000313|EMBL:EOH90738.1, ECO:0000313|Proteomes:UP000013777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700915 {ECO:0000313|EMBL:EOH90738.1,
RC ECO:0000313|Proteomes:UP000013777};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus asini ATCC_700915.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH90738.1}.
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DR EMBL; AJAP01000004; EOH90738.1; -; Genomic_DNA.
DR RefSeq; WP_010753138.1; NZ_KB946293.1.
DR AlphaFoldDB; R2Q625; -.
DR STRING; 57732.RU94_GL000038; -.
DR GeneID; 78363871; -.
DR PATRIC; fig|1158606.3.peg.452; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_1_2_9; -.
DR OrthoDB; 43195at2; -.
DR Proteomes; UP000013777; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01544; PBP1_GalR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF151; HTH-TYPE TRANSCRIPTIONAL REPRESSOR MELR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000013777};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 345 AA; 38718 MW; AF60D56A9AF9B63F CRC64;
MATITDIARA AEVSISTVSR VLNYDPTLSV TEETKRKIFE AAENLNYTKY KVKQKNRQPV
EKKESQTSIG IIQWRLDDEE LEDIYYMSIR LGVEKRAAEL GYTVVKFSQI DESIAQSVDG
LLAIGKFTQE TIDKLRNLHA NLCVIGSNFP LNDYDSVNTD FSQATELALQ HLLDLGHKKI
AFIGAEESKN MYGFRRYKTP TANTFRDIMR SQGLLDEDYF IMRDNSRLDV ATGEALTQFA
LEQWQDELPT AILAANDAFA IGVIHTLKAR NIKIPKDISV MGINDISISQ YVSPPLSSVK
AFTEHMGEAA VDLLAKRIKS PVVAQRIFLS TELVVRDSTG KPRAN
//
