ID   R2S0F9_9ENTE            Unreviewed;      1352 AA.
AC   R2S0F9;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=LPXTG-domain-containing protein cell wall anchor domain {ECO:0000313|EMBL:EOH86306.1};
GN   ORFNames=UAU_05228 {ECO:0000313|EMBL:EOH86306.1};
OS   Enterococcus pallens ATCC BAA-351.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1158607 {ECO:0000313|EMBL:EOH86306.1, ECO:0000313|Proteomes:UP000013782};
RN   [1] {ECO:0000313|EMBL:EOH86306.1, ECO:0000313|Proteomes:UP000013782}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-351 {ECO:0000313|EMBL:EOH86306.1,
RC   ECO:0000313|Proteomes:UP000013782};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Enterococcus pallens BAA-351.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the serine-aspartate repeat-containing protein
CC       (SDr) family. {ECO:0000256|ARBA:ARBA00007257}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOH86306.1}.
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DR   EMBL; AJAQ01000054; EOH86306.1; -; Genomic_DNA.
DR   RefSeq; WP_010760147.1; NZ_KB946302.1.
DR   STRING; 160454.RV10_GL002365; -.
DR   PATRIC; fig|1158607.3.peg.5201; -.
DR   eggNOG; COG4932; Bacteria.
DR   HOGENOM; CLU_005681_1_0_9; -.
DR   OrthoDB; 2216808at2; -.
DR   Proteomes; UP000013782; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.3930; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR041033; Prealbumin-like.
DR   InterPro; IPR041100; TQ.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   PANTHER; PTHR36108:SF13; COLOSSIN-B; 1.
DR   PANTHER; PTHR36108; COLOSSIN-B-RELATED; 1.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   Pfam; PF17802; SpaA; 6.
DR   Pfam; PF18202; TQ; 1.
DR   SUPFAM; SSF49478; Cna protein B-type domain; 1.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE   3: Inferred from homology;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013782};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..1352
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039419790"
FT   TRANSMEM        1327..1346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1318..1352
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|PROSITE:PS50847"
FT   REGION          36..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..75
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..96
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1352 AA;  150573 MW;  7014A8FAB817E33C CRC64;
     MNKFKKILMS LMLLFSLSGQ LAPSVQVLAE VQKTEVSSSS EVVEEVETKE VTKKTTDTKE
     STKTSETEEV QTEKPEIGKS QNSNDSPKVT VDDHQVPTNQ LADILDQYGY YMTEDGKFLS
     RTNETIRDNW NEFLEKVQEV QGNSQVGRSL SPLTRAGVTI YVDQNYSIPT ASWDYSSGIH
     DSGFYAKRDA NGGMLWCVAP GNPLNFGANG GFTPEERDQL NLVIASLIAY WGYETQPSVA
     NAFYTERHIQ RMASAVSTSN IQDPSGTVSQ AGYEAWVKET DRKINSFLTK PSFDTKSFTM
     KKGDTLRIDD VNSSLWAYKV ATNDTNMNVS IDGNTLVIKA TGDVKDGTIQ LKYNIPTSYQ
     GATLVYRHPY SQELLQAAIK DPNITKVNIK VLKNGNAKIK KVDADTGKAI SGAKFKLSYD
     GKQVEVVTNA TGEAELKDIT HGTKVTIQEI QAANGYVINQ TPQTVTIEAD QTVTAIFKNK
     KQVGRLDLIK EDKETGNQPQ GSAKLDGAVY GLFETNGQKV KEVTLKQTGD KVTGSFENIQ
     IMHDYYVQEI KAPEGYNVDG TKYPVNIAYA GQDQTVAVQS MSLKDQVIKG GVEIVKIGNK
     PLVNQVLDKL TGKSDNVKPK LEGAEFTITS KTTGKPVKVI ITDKDGKAST GKTLPYDSYI
     MTETKTPEGY LTIEPIEFTV SEEDQTFFWV LEDKIIESQL QLIKVDAETG KNIPLRDTTF
     KIWDRLANDG EGGYVSMRVP NSLEVSDEFK TNEKGELVTN DSLPFGKDRY EIRELRAPEG
     YLLATEPVVF SVTEADAGGV ITIKFKNMPQ KGQVKIHKTG EKGISAVEKE SEYGKYAEIQ
     YDQVDLANVK FKIRAAEDIT TPDGTVRLAK GDYIQKDGKD LELVTDDSGM TSSDPNLYLG
     KYEAIEIEAP NGFVMLEEPI PFEINYEGQL VELASTDVKV ENTLQKIDVY GYKKQEVVTG
     WEDGKPTIEL EDAKNDQVFG LYVGEEGIQI GFTILPHDTA LAFVKVKDGK LAFEGLTLPN
     VESNFYIKEI DAGNDHVLDE THYGFQYVPS TNQKEHTIHV FADGYAENKE ILTKMARKEI
     ENKLAYTDVE LVKTDNLGNK PLEGVEFQLI REDDKKETVV DTYKTDKDGK IIVEKLPTGN
     YRFKETKPLS WYYPNEDDLS FEVTPETNGQ VISLKAVNKR KPMEITTFLA TVDGNKEADP
     TVDNILRDEV EIKGAEVGHT YSIVTPYVDP ETKKVITTVE STYTAEAENE TIQVDIPIEK
     NTMKDGQKGV ATHYIYYDKE KTKEIGKEDN LENTDQMVTF KERKVFPKTT TVSKTKTLPK
     TNDSQNIFMS VIGLILLVGV SVVVFVRRKT CK
//