ID R3TMI9_9ENTE Unreviewed; 328 AA.
AC R3TMI9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit {ECO:0000313|EMBL:EOL42729.1};
GN ORFNames=UC3_03082 {ECO:0000313|EMBL:EOL42729.1};
OS Enterococcus phoeniculicola ATCC BAA-412.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158610 {ECO:0000313|EMBL:EOL42729.1, ECO:0000313|Proteomes:UP000013785};
RN [1] {ECO:0000313|EMBL:EOL42729.1, ECO:0000313|Proteomes:UP000013785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-412 {ECO:0000313|EMBL:EOL42729.1,
RC ECO:0000313|Proteomes:UP000013785};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus phoeniculicola BAA-412.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOL42729.1}.
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DR EMBL; AJAT01000017; EOL42729.1; -; Genomic_DNA.
DR RefSeq; WP_010769716.1; NZ_KB946329.1.
DR AlphaFoldDB; R3TMI9; -.
DR STRING; 154621.RV11_GL003052; -.
DR PATRIC; fig|1158610.3.peg.3066; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_9; -.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000013785; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000013785}.
FT DOMAIN 4..180
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 328 AA; 35984 MW; 8ECA4619B8A96B7B CRC64;
MAEMTYLEAI NLGISEEMSR DEKVVIFGED VGGEKGGVFG VTKGLAAKFG DDRCFNTPLT
EGLIGGLAIG LGLRGYRAIG EFQFADYILP ATNQILSEAR TMRYRTKGDW TAPIVYRTPY
GGGVRGGLYH SQSTEKIFCG QPGLRVVTPS NPYDAKGMIK AAIRSDDPVI FYEHKRLYRL
LKDEVPTDDY IVPIDKANVV RQGSDITVIG YGMMLQYILS AAEKLAQEGI EVEVVDVRSL
YPLDRETLVN AAKKTGKVLL VTEDNKEGSV MSEIAAMISE DALFDLDAPI QRLAGPDAPS
MGYALPLERE FLVNEEQVTT AMRELAAF
//
