ID R3TPU1_9ENTE Unreviewed; 599 AA.
AC R3TPU1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=LPXTG-domain-containing protein cell wall anchor domain {ECO:0000313|EMBL:EOL43103.1};
GN ORFNames=UC3_02080 {ECO:0000313|EMBL:EOL43103.1};
OS Enterococcus phoeniculicola ATCC BAA-412.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158610 {ECO:0000313|EMBL:EOL43103.1, ECO:0000313|Proteomes:UP000013785};
RN [1] {ECO:0000313|EMBL:EOL43103.1, ECO:0000313|Proteomes:UP000013785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-412 {ECO:0000313|EMBL:EOL43103.1,
RC ECO:0000313|Proteomes:UP000013785};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus phoeniculicola BAA-412.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
CC -!- SIMILARITY: Belongs to the serine-aspartate repeat-containing protein
CC (SDr) family. {ECO:0000256|ARBA:ARBA00007257}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOL43103.1}.
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DR EMBL; AJAT01000016; EOL43103.1; -; Genomic_DNA.
DR RefSeq; WP_010768742.1; NZ_KB946328.1.
DR AlphaFoldDB; R3TPU1; -.
DR STRING; 154621.RV11_GL003079; -.
DR PATRIC; fig|1158610.3.peg.2076; -.
DR eggNOG; COG4932; Bacteria.
DR HOGENOM; CLU_019685_1_0_9; -.
DR OrthoDB; 2194620at2; -.
DR Proteomes; UP000013785; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005518; F:collagen binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.1280; -; 1.
DR Gene3D; 2.60.40.740; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR InterPro; IPR008456; Collagen-bd_dom.
DR InterPro; IPR011252; Fibrogen-bd_dom1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR041171; SDR_Ig.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR36108:SF13; COLOSSIN-B; 1.
DR PANTHER; PTHR36108; COLOSSIN-B-RELATED; 1.
DR Pfam; PF17961; Big_8; 1.
DR Pfam; PF05737; Collagen_bind; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17802; SpaA; 2.
DR SUPFAM; SSF49401; Bacterial adhesins; 2.
DR SUPFAM; SSF49478; Cna protein B-type domain; 2.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000013785};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 579..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 569..599
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 506..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 64862 MW; B4D9FBED95D7FD53 CRC64;
MQMKRKSLIS SLVIFLGLIS QLFISVPALA AVDYGEQLLT HSELQDEYGN AKDHFTLYDT
MVAHYDFVIP DDVAIHNGDS MTISLPPELV ISGSLGFAVT DDSGNIVGQA TVDKESGKVV
IVFTDYYETH PNDKKGSFNV YTQWNKENVT SNQDVEVNLG TGGSTIHIDE DPGVGSDEKL
SKWGWVDDND PTLIHWVVRV NFEGNEIQNA VYTDYIGANQ LLVPGTANAT LGYFDANNTF
IWEDDLDSSK ISEAADGLSF TVNYGTLEKS SVIYYDTKAT DNGLSSQYEN SGKLTGSNIE
EVTISVYTPK TGGNGNGSGA NQSVLLTKKD AATSQVLDGA MFKLLDANGN LIKENLITDA
NGQLKVEGLA SGNYFFVETK APAGYLLDNT PLSFEIVKNQ ETAVQVEMTN IKAFGQVILT
KIDGKTGLEL SGALFELQDQ KGTSLQENLR TDKNGQIHIT NLAPGEYQFI ETQAPDGYQL
DQKPVKFTIK KNDETIVYVS KENTLLPTVP TPSESSTTES TTSESASSES ETTESSTSYS
STGASSVSDD SSSRSSSSSS FERNKTTHLP KTGEHLTKGL TILGGSLLLL TGIYLFKRP
//
