ID   R3WIR0_9ENTE            Unreviewed;       491 AA.
AC   R3WIR0;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=PRD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=UC3_03345 {ECO:0000313|EMBL:EOL41780.1};
OS   Enterococcus phoeniculicola ATCC BAA-412.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1158610 {ECO:0000313|EMBL:EOL41780.1, ECO:0000313|Proteomes:UP000013785};
RN   [1] {ECO:0000313|EMBL:EOL41780.1, ECO:0000313|Proteomes:UP000013785}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-412 {ECO:0000313|EMBL:EOL41780.1,
RC   ECO:0000313|Proteomes:UP000013785};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Enterococcus phoeniculicola BAA-412.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOL41780.1}.
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DR   EMBL; AJAT01000018; EOL41780.1; -; Genomic_DNA.
DR   RefSeq; WP_010769976.1; NZ_KB946329.1.
DR   AlphaFoldDB; R3WIR0; -.
DR   STRING; 154621.RV11_GL002692; -.
DR   PATRIC; fig|1158610.3.peg.3338; -.
DR   eggNOG; COG3711; Bacteria.
DR   HOGENOM; CLU_013442_2_1_9; -.
DR   OrthoDB; 3239954at2; -.
DR   Proteomes; UP000013785; Unassembled WGS sequence.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd05568; PTS_IIB_bgl_like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.1790.10; PRD domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR007737; Mga_HTH.
DR   InterPro; IPR011608; PRD.
DR   InterPro; IPR036634; PRD_sf.
DR   InterPro; IPR036095; PTS_EIIB-like_sf.
DR   InterPro; IPR013011; PTS_EIIB_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR   PANTHER; PTHR30185:SF18; TRANSCRIPTIONAL REGULATOR MTLR; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   Pfam; PF05043; Mga; 1.
DR   Pfam; PF00874; PRD; 1.
DR   SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR   SUPFAM; SSF63520; PTS-regulatory domain, PRD; 2.
DR   PROSITE; PS51372; PRD_2; 2.
DR   PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000013785};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          177..289
FT                   /note="PRD"
FT                   /evidence="ECO:0000259|PROSITE:PS51372"
FT   DOMAIN          292..399
FT                   /note="PRD"
FT                   /evidence="ECO:0000259|PROSITE:PS51372"
FT   DOMAIN          400..491
FT                   /note="PTS EIIB type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51099"
SQ   SEQUENCE   491 AA;  57387 MW;  0AC1E625ADDBDFE4 CRC64;
     MKLSKKESEL LELFVLKDTK LTAKEIAESL NISSKTVYRL VHKINEASEF GILIETYIGK
     GMKMNYRNYL KYRSIFKQSG SETEERVSSV LMNLLSSSPL FISIENLFKR YFISSETQYK
     DLEKIKKKMK QFDLLLERKE NKIRIIGKEQ SIRKAIYHML LRTAIVDTDF YVIDNKNISQ
     YDIDFLTAQL ELIEKKIKGN IPYPYNINIF SHLYILVMRI RNGFIPKNRE DKTLDAYEVS
     LKESNQEIYG ISQKIVGNLS HYLSEKIDQI EEFYLFQYII SSGIEEQSFE LYSDGQLKLI
     FEDAIDFVSQ HMALDFSSLK EDKSFFNHFR VMLYRNKNKI VIVNNLLGEI KKEYPELFKS
     VEKLSHYLSS EYSLAPISED ESGFTMLYFA KDFEKLKTKK RVIIMCSSGV GTSELLKVKV
     QRNFPTLDII DVVSVNQFKK KYMEEKVIVD FIISTINITL YNLILEVPVA LVSAMFTGKD
     QETIRLMMEG I
//