ID R4FLC9_RHOPR Unreviewed; 486 AA.
AC R4FLC9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Putative rhogap-p50rhogap: rhogap gtpase-activator protein {ECO:0000313|EMBL:JAA76042.1, ECO:0000313|EnsemblMetazoa:RPRC014495-PA};
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EMBL:JAA76042.1};
RN [1] {ECO:0000313|EMBL:JAA76042.1}
RP NUCLEOTIDE SEQUENCE.
RA Ribeiro J.M.C., Genta F.A., Sorgine M.H.F., Paiva-Silva G.O.,
RA Majerowicz D., Medeiros M., Koerich L., Terra W.R., Ferreira C.,
RA Pimentel A.C., Bisch P.M., Diniz M.M.P., Nascimento R., Salmon D.,
RA Silber A.M., Alves M., Oliveira M.F., Gondim K.C., Silva Neto M.A.C.,
RA Atella G.C., Araujo H., Dias F.S., Polycarpo C.R., Fampa P., Melo A.C.,
RA Tanaka A.S., Balczun C., Oliveira J.H.M., Goncalves R., Lazoski C.,
RA Pereira M.A., Rivera-Pomar R., Diambra L., Schaub G.A., Garcia E.S.,
RA Azambuja P., Braz G.R.C., Oliveira P.L.;
RT "An insight into the transcriptome of the digestive tract of the blood
RT sucking bug, Rhodnius prolixus.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:RPRC014495-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
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DR EMBL; ACPB03000235; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GAHY01001468; JAA76042.1; -; mRNA.
DR AlphaFoldDB; R4FLC9; -.
DR STRING; 13249.R4FLC9; -.
DR EnsemblMetazoa; RPRC014495-RA; RPRC014495-PA; RPRC014495.
DR VEuPathDB; VectorBase:RPRC014495; -.
DR eggNOG; KOG4406; Eukaryota.
DR HOGENOM; CLU_030214_0_0_1; -.
DR InParanoid; R4FLC9; -.
DR OMA; PTRVREY; -.
DR OrthoDB; 3030820at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000015103}.
FT DOMAIN 106..261
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 298..484
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 486 AA; 55474 MW; 5D4E1F1C0152F48E CRC64;
MADSNFANTA ATKNVLCLQN DVEDLYPSLS DPHDHEPNLE FDDTELQNAT TVNEEKIDMC
STYDYLESPV SDGTIEENFE VELENAPTGG GYDSLTCTLD EYSDDDFSDV SKFGIVEVYG
DDTAGRRIIV VSACMLPSNK ELDHSRLLRY LMFTLSRFVE QDYSLVYFHY GLNSKNKPSL
SWLWHAYKQF DRKYKKNLKA LYLVHPTNFI RIVWQIFKAA ISVKFGRKMM YVNYLHELRE
HLNLDQIRIP QPVLEHDERL LSKLKKGACT AAVSVQASPS LAGEFEILQP LATQQFGVSL
QFIKDNNNGQ VIPPIVRQCV DFLTTPDALE TEGLFRRSAN VTVVKDMQAK INNGQEVDFN
GDVHIAAVLL KTFLRELEEP LMTFDLYDEI TLFPNISKDE RPRHVKILIL EKLPEDNYKV
LKYIVQFLSK VMDRCDLNKM TSSNLAVVFG PNLIRSPNGQ LSLSAISPIN MFTDFVLVNQ
DQIFII
//
