ID R4FMR4_RHOPR Unreviewed; 507 AA.
AC R4FMR4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Putative polynucleotide kinase 3' phosphatase {ECO:0000313|EMBL:JAA75891.1, ECO:0000313|EnsemblMetazoa:RPRC007937-PA};
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EMBL:JAA75891.1};
RN [1] {ECO:0000313|EMBL:JAA75891.1}
RP NUCLEOTIDE SEQUENCE.
RA Ribeiro J.M.C., Genta F.A., Sorgine M.H.F., Paiva-Silva G.O.,
RA Majerowicz D., Medeiros M., Koerich L., Terra W.R., Ferreira C.,
RA Pimentel A.C., Bisch P.M., Diniz M.M.P., Nascimento R., Salmon D.,
RA Silber A.M., Alves M., Oliveira M.F., Gondim K.C., Silva Neto M.A.C.,
RA Atella G.C., Araujo H., Dias F.S., Polycarpo C.R., Fampa P., Melo A.C.,
RA Tanaka A.S., Balczun C., Oliveira J.H.M., Goncalves R., Lazoski C.,
RA Pereira M.A., Rivera-Pomar R., Diambra L., Schaub G.A., Garcia E.S.,
RA Azambuja P., Braz G.R.C., Oliveira P.L.;
RT "An insight into the transcriptome of the digestive tract of the blood
RT sucking bug, Rhodnius prolixus.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:RPRC007937-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
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DR EMBL; ACPB03023273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GAHY01001619; JAA75891.1; -; mRNA.
DR AlphaFoldDB; R4FMR4; -.
DR STRING; 13249.R4FMR4; -.
DR EnsemblMetazoa; RPRC007937-RA; RPRC007937-PA; RPRC007937.
DR VEuPathDB; VectorBase:RPRC007937; -.
DR eggNOG; KOG2134; Eukaryota.
DR HOGENOM; CLU_014938_1_1_1; -.
DR InParanoid; R4FMR4; -.
DR OMA; RAKNWAP; -.
DR OrthoDB; 5490169at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041388; FHA_2.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006549; HAD-SF_hydro_IIIA.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013954; PNK3P.
DR InterPro; IPR006551; Polynucleotide_phosphatase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR NCBIfam; TIGR01664; DNA-3'-Pase; 1.
DR NCBIfam; TIGR01662; HAD-SF-IIIA; 1.
DR PANTHER; PTHR12083; BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE; 1.
DR PANTHER; PTHR12083:SF9; BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF17913; FHA_2; 1.
DR Pfam; PF08645; PNK3P; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000313|EMBL:JAA75891.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW Transferase {ECO:0000313|EMBL:JAA75891.1}.
FT DOMAIN 8..83
FT /note="PNK FHA"
FT /evidence="ECO:0000259|Pfam:PF17913"
SQ SEQUENCE 507 AA; 58229 MW; 99B66EF5A5ECAC82 CRC64;
MVDVNVKCYL VPKESLSVEW MIKEIDLPNL QEITIGRGKE YGIMDLACSK EQLLLEADTA
ARMVKIRRVG RNPSILAGFP LEQNQVYIAR EGMVLQITPE IVYTVTFEAL QQNKRENEEK
ILPEVKKLAK KFTWSIIPSG TVITCMTNEV NFSLRKIAGF DLDGTLITTK SGHTFPSNDD
DWKLWHSVVK NRLKTLVTEG YSLVLFTNQA QLEISSTSRK ESFKKKIENI MNALDVPFMV
LIATARDVFR KPAPGMWDYY ISKTQGKIDI NSSFYVGDAA GRVAEKQKKS DFDITDRLFA
RNIGVKFYTP DEFFLNESPR TFKDVDFHPQ ETSEEDYPEL YIPSKPSELI VMVGSPASGK
SYFARNILKP KGYIIISRDE LKVWTKCRDK IISAISNQQN VVYDATNPDK ESRKTILDVC
LLKNFTNIRC FMMTTFEERC VHNNRFRQLV NNSNPVPHTA IITFGKRFEK PTLAEGFKSV
VKIPFVPHFQ CLEHEQLYKK YLLGRKK
//
