ID R4G3Z2_RHOPR Unreviewed; 362 AA.
AC R4G3Z2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Putative aldo/keto reductase family protein {ECO:0000313|EMBL:JAA75715.1, ECO:0000313|EnsemblMetazoa:RPRC009854-PA};
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EMBL:JAA75715.1};
RN [1] {ECO:0000313|EMBL:JAA75715.1}
RP NUCLEOTIDE SEQUENCE.
RA Ribeiro J.M.C., Genta F.A., Sorgine M.H.F., Paiva-Silva G.O.,
RA Majerowicz D., Medeiros M., Koerich L., Terra W.R., Ferreira C.,
RA Pimentel A.C., Bisch P.M., Diniz M.M.P., Nascimento R., Salmon D.,
RA Silber A.M., Alves M., Oliveira M.F., Gondim K.C., Silva Neto M.A.C.,
RA Atella G.C., Araujo H., Dias F.S., Polycarpo C.R., Fampa P., Melo A.C.,
RA Tanaka A.S., Balczun C., Oliveira J.H.M., Goncalves R., Lazoski C.,
RA Pereira M.A., Rivera-Pomar R., Diambra L., Schaub G.A., Garcia E.S.,
RA Azambuja P., Braz G.R.C., Oliveira P.L.;
RT "An insight into the transcriptome of the digestive tract of the blood
RT sucking bug, Rhodnius prolixus.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:RPRC009854-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
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DR EMBL; ACPB03015538; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GAHY01001795; JAA75715.1; -; mRNA.
DR AlphaFoldDB; R4G3Z2; -.
DR STRING; 13249.R4G3Z2; -.
DR EnsemblMetazoa; RPRC009854-RA; RPRC009854-PA; RPRC009854.
DR VEuPathDB; VectorBase:RPRC009854; -.
DR eggNOG; KOG1577; Eukaryota.
DR HOGENOM; CLU_023205_0_0_1; -.
DR InParanoid; R4G3Z2; -.
DR OMA; LMECANI; -.
DR OrthoDB; 890110at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0044281; P:small molecule metabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43827; 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; 1.
DR PANTHER; PTHR43827:SF3; ALDO-KETO REDUCTASE; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00798; ALDOKETO_REDUCTASE_1; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
DR PROSITE; PS00063; ALDOKETO_REDUCTASE_3; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000015103}.
FT DOMAIN 63..336
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 362 AA; 40768 MW; 7ABCD05A25DF239C CRC64;
MTGLTTATNL TLKVLNKRRY PAISQTRNNF FKKLFGKKKS SEYDSNLTPC SRIETRGMSM
PMIGIGTWQV EPDCIESVIT CALTVGYRHI DTSHSYGNQA AIGATLDSLF KGGKFCRNEI
FISSKLPYYG MKPEEICNYV TDALNCLCLQ YIDLFMIQFP VGIKEIGGNY IADPDTNHIL
IWKALEEEVK KDRIKSLGLS NFNMRQISTL MECANIPPAN LQVEMHLYLQ QKELITFCSQ
HCIGMTAYAP LGSPGLDQYL MKNSLQPASV PSPLNDNSVI SVACNHKKTP AQVLLRFLLQ
SGVAVIPKSV LPDRIYKNFD IFDFNLDKCE MDELRGKDLC EKGRMFGSNI WVGTDHHPEF
PF
//
