ID   R4G8D2_RHOPR            Unreviewed;       222 AA.
AC   R4G8D2;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EMBL:JAA76333.1};
RN   [1] {ECO:0000313|EMBL:JAA76333.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ribeiro J.M.C., Genta F.A., Sorgine M.H.F., Paiva-Silva G.O.,
RA   Majerowicz D., Medeiros M., Koerich L., Terra W.R., Ferreira C.,
RA   Pimentel A.C., Bisch P.M., Diniz M.M.P., Nascimento R., Salmon D.,
RA   Silber A.M., Alves M., Oliveira M.F., Gondim K.C., Silva Neto M.A.C.,
RA   Atella G.C., Araujo H., Dias F.S., Polycarpo C.R., Fampa P., Melo A.C.,
RA   Tanaka A.S., Balczun C., Oliveira J.H.M., Goncalves R., Lazoski C.,
RA   Pereira M.A., Rivera-Pomar R., Diambra L., Schaub G.A., Garcia E.S.,
RA   Azambuja P., Braz G.R.C., Oliveira P.L.;
RT   "An insight into the transcriptome of the digestive tract of the blood
RT   sucking bug, Rhodnius prolixus.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GAHY01001177; JAA76333.1; -; mRNA.
DR   AlphaFoldDB; R4G8D2; -.
DR   VEuPathDB; VectorBase:RPRC012226; -.
DR   HOGENOM; CLU_2029560_0_0_1; -.
DR   CDD; cd13288; PH_Ses; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR045188; Boi1/Boi2-like.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR22902:SF27; INOSITOL PHOSPHATASE INTERACTING PROTEIN, ISOFORM A; 1.
DR   PANTHER; PTHR22902; SESQUIPEDALIAN; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          17..113
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          137..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..172
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   222 AA;  25939 MW;  D84AAD6C5176BAA4 CRC64;
     MKINDKNLSA FAVSLNGIDR EGWLVKRGEI NKAFQKRWFV LKGNLLFYFD KRYDKEPTGV
     IILEGCTIEL AEDDGQFGFK IVFHGQGNRT YVLVADSQDS MEQWMKALAC ASYDYIKLMV
     SELQRQLEEM EVNVPLSNED NSCGHPVPPP RTRHNPFNRT LTTGSHSRSH SIRSAPGRTD
     HDSYRQKITF RELHNIYSRR ILQDFNEWKY QQRQLQQPLI QL
//