ID R4KGA4_CLOPA Unreviewed; 845 AA.
AC R4KGA4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase {ECO:0000313|EMBL:AGK98645.1};
GN ORFNames=Clopa_3896 {ECO:0000313|EMBL:AGK98645.1};
OS Clostridium pasteurianum BC1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=86416 {ECO:0000313|EMBL:AGK98645.1, ECO:0000313|Proteomes:UP000013523};
RN [1] {ECO:0000313|EMBL:AGK98645.1, ECO:0000313|Proteomes:UP000013523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1 {ECO:0000313|EMBL:AGK98645.1,
RC ECO:0000313|Proteomes:UP000013523};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Dunn J.,
RA Taghavi S., Francis A., van der Lelie D., Woyke T.;
RT "Complete sequence of chromosome of Clostridium pasteurianum BC1.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003261; AGK98645.1; -; Genomic_DNA.
DR RefSeq; WP_015616920.1; NC_021182.1.
DR AlphaFoldDB; R4KGA4; -.
DR STRING; 86416.Clopa_3896; -.
DR KEGG; cpas:Clopa_3896; -.
DR PATRIC; fig|86416.3.peg.3891; -.
DR eggNOG; COG0737; Bacteria.
DR HOGENOM; CLU_005854_7_3_9; -.
DR OrthoDB; 9800780at2; -.
DR Proteomes; UP000013523; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008252; F:nucleotidase activity; IEA:UniProt.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR InterPro; IPR008334; 5'-Nucleotdase_C.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006146; 5'-Nucleotdase_CS.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR11575:SF48; 5' NUCLEOTIDASE, ECTO-LIKE; 1.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR Pfam; PF02872; 5_nucleotid_C; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR01607; APYRASEFAMLY.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS00786; 5_NUCLEOTIDASE_2; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Hydrolase {ECO:0000313|EMBL:AGK98645.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000013523};
KW Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..845
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004374665"
FT TRANSMEM 821..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..256
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 348..517
FT /note="5'-Nucleotidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02872"
FT DOMAIN 804..844
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|Pfam:PF00746"
SQ SEQUENCE 845 AA; 88725 MW; F17D9D1D35B640BC CRC64;
MKTKFFKKHL MLTMVLAMIL SVLSIQSYAL ADVSQTSTQI TIFHTNDMHG HLLDAFNTAK
PPVLTQIGSD YTAAIKKSVP NSLLIDAGDA TQGVPFATIS KGADIIKLMN AAGYDGMVLG
NHEFDYGKDQ ALANAKLASF PVVSANTMQN GQPFLAGVNG NNGEDFIKTV NGIKVGFFGI
TTQETEYKTN PSNLSGITFE DPIATSKSEV SKLKSEGVKV IVGIMHIGND PSSDPTSEDI
AKAVDGINVI IDGHSHTIEN KLVNNALIAQ TGCYNANLGR LDISVTNDGK VSATESLISA
ASATTNYTPD SSVKDLATQI NASQAPIFAQ IVGRTNTSFW AGTVNGQSVA RLGETNLGDL
VADAMADGAK SQVKGTEFAS LPIVALENGG GVRDSIPVGD INQGQITTVL PFGNILSLKE
VTPSLLYQTL ENGVSKVSVP DTSTGIVTGA DGRFPQISGM RFEYNPQNAA SNRISKIVLL
NADGSDRQVL DKNDTNTKIV LASNDYEVGG GDGYTMLGGL KNIGEGNALD VITSQYITKL
TLQNGGTFSY PAYQGRIKIS SNFIYKPYTA AITVKNGADL LSNTAVTYAM DNGNPVHTTT
DANGILTIAN VPSGPHNVSI LYNNLAVDSY INDIIGSNTA EKVIASLVTI DPAIPKETSD
MIAALPSNIT LSNKDAVASA RASYDRLTLA QKSLVTNYSK LTSAEATIAD LTEIMKDKTA
ADVVTAKINA IPLTVTASDK DAVAAARTAY DALTPAQKAL VINYNTLTSA ENTLVKLSTS
ENNQEVSKDA ADTESVTANK ASTAPKIAVL PKTGSPLDTT GLVGFGSLLM LSGLGVLSYK
RKAEN
//
