ID   R4XBY7_TAPDE            Unreviewed;       270 AA.
AC   R4XBY7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Protein BIG1 {ECO:0000256|ARBA:ARBA00022089};
GN   ORFNames=TAPDE_000498 {ECO:0000313|EMBL:CCG80855.1};
OS   Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563
OS   / JCM 9778 / NBRC 8474) (Peach leaf curl fungus) (Lalaria deformans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Taphrinomycetes;
OC   Taphrinales; Taphrinaceae; Taphrina.
OX   NCBI_TaxID=1097556 {ECO:0000313|EMBL:CCG80855.1, ECO:0000313|Proteomes:UP000013776};
RN   [1] {ECO:0000313|EMBL:CCG80855.1, ECO:0000313|Proteomes:UP000013776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 /
RC   NBRC 8474 {ECO:0000313|Proteomes:UP000013776};
RX   PubMed=23631913; DOI=10.1128/mBio.00055-13;
RA   Cisse O.H., Almeida J.M.G.C.F., Fonseca A., Kumar A.A., Salojaervi J.,
RA   Overmyer K., Hauser P.M., Pagni M.;
RT   "Genome sequencing of the plant pathogen Taphrina deformans, the causal
RT   agent of peach leaf curl.";
RL   MBio 4:e00055-e00013(2013).
CC   -!- SIMILARITY: Belongs to the BIG1 family.
CC       {ECO:0000256|ARBA:ARBA00008203}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCG80855.1}.
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DR   EMBL; CAHR02000016; CCG80855.1; -; Genomic_DNA.
DR   AlphaFoldDB; R4XBY7; -.
DR   STRING; 1097556.R4XBY7; -.
DR   VEuPathDB; FungiDB:TAPDE_000498; -.
DR   eggNOG; ENOG502S6TD; Eukaryota.
DR   Proteomes; UP000013776; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR037654; Big1.
DR   InterPro; IPR046756; VAS1/VOA1_TM.
DR   PANTHER; PTHR28285; PROTEIN BIG1; 1.
DR   PANTHER; PTHR28285:SF1; PROTEIN BIG1; 1.
DR   Pfam; PF20520; Ac45-VOA1_TM; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013776};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..270
FT                   /note="Protein BIG1"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004381432"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          222..260
FT                   /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF20520"
SQ   SEQUENCE   270 AA;  29369 MW;  DF5217E03F5EE40C CRC64;
     MRTFGIASLL VAVTQAFEDT SPLLYLSSNQ HVVPGHSSSS MLAASTFRAS ALAALSCDIS
     NTIVAIQPSI HASDFTEDAA PMIRQYLTQA GTKMVVPYGH GEIDSDEVIA HIANQCNAKI
     ERVDASTMSH PVYESDEKRV IAITFPTLPL SSEQRKVALN DNDAFLHSLL RSFPTRDYNL
     LYLSTPPPAS PASFRRAHVA LGDLLPQKSS NSSTGGLFSH YQFFTPGIFM GYMVLLILVP
     VLIIGLQALN SLQISYKAFD PPLKIGQKQQ
//