ID   R5A7X9_9FIRM            Unreviewed;       372 AA.
AC   R5A7X9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Methionine synthase II (Cobalamin-independent) {ECO:0000313|EMBL:CCX39330.1};
GN   ORFNames=BN453_00278 {ECO:0000313|EMBL:CCX39330.1};
OS   Firmicutes bacterium CAG:102.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262998 {ECO:0000313|EMBL:CCX39330.1, ECO:0000313|Proteomes:UP000018112};
RN   [1] {ECO:0000313|EMBL:CCX39330.1, ECO:0000313|Proteomes:UP000018112}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:102 {ECO:0000313|EMBL:CCX39330.1,
RC   ECO:0000313|Proteomes:UP000018112};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX39330.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAWG010000024; CCX39330.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5A7X9; -.
DR   STRING; 1262998.BN453_00278; -.
DR   Proteomes; UP000018112; Unassembled WGS sequence.
DR   GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR   CDD; cd03311; CIMS_C_terminal_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR002629; Met_Synth_C/arc.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF01717; Meth_synt_2; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018112}.
FT   DOMAIN          13..367
FT                   /note="Cobalamin-independent methionine synthase MetE C-
FT                   terminal/archaeal"
FT                   /evidence="ECO:0000259|Pfam:PF01717"
SQ   SEQUENCE   372 AA;  42066 MW;  6980D02EF001BD96 CRC64;
     MSNLQTPFRY DFVGSFLRPQ ALKDAKAAYQ AGEISKEAFD RVAEEEVAKV VAKQKELGYH
     VITDGEFRRA FWHLDFMWGF EGVAHEDTGN GVQFDAELAL LEDTYLVGKI KAKAHPFVEY
     FKFLKQFEDE NTVAKYTIPA PAQTFQQMIV PANYERTRKI YATNEELIQD IGKAYQDVIQ
     QFYDAGCRNL QFDDCTWGAI VGDAAEQRYQ ALGIDLNDVK AQLLAVNNLA LEGKPADMII
     NSHICRGNYH STYFTSGPYD SVADYVFAKE NVNALFLEYD DERSGGFAPL AKVSADKKVV
     LGLITTKTPE LEEKERIIAR IHEAAKYIPL DRLCLSPQCG FASCEIGNKL TEEEQWAKLK
     LVKEIAEEVW GK
//