ID R5AHL1_9CLOT Unreviewed; 558 AA.
AC R5AHL1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Iron only hydrogenase large subunit C-terminal domain {ECO:0000313|EMBL:CCX42323.1};
GN ORFNames=BN454_01588 {ECO:0000313|EMBL:CCX42323.1};
OS Clostridium sp. CAG:1024.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262770 {ECO:0000313|EMBL:CCX42323.1, ECO:0000313|Proteomes:UP000017946};
RN [1] {ECO:0000313|EMBL:CCX42323.1, ECO:0000313|Proteomes:UP000017946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:1024 {ECO:0000313|Proteomes:UP000017946};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX42323.1}.
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DR EMBL; CAWJ010000226; CCX42323.1; -; Genomic_DNA.
DR AlphaFoldDB; R5AHL1; -.
DR STRING; 1262770.BN454_01588; -.
DR Proteomes; UP000017946; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 1.10.15.40; Electron transport complex subunit B, putative Fe-S cluster; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR007202; 4Fe-4S_dom.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR PANTHER; PTHR11615:SF368; HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF04060; FeS; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS51656; 4FE4S; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017946}.
FT DOMAIN 3..30
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 32..61
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 345..406
FT /note="4Fe-4S"
FT /evidence="ECO:0000259|PROSITE:PS51656"
SQ SEQUENCE 558 AA; 61907 MW; 3351C3E04A57C701 CRC64;
MAEFLKLKRS NCKNCYRCIR ACPVKSIRFS AGQANIVGDE CILCGQCFVV CPQNAKEIAS
GVEQVKVLLA GNAPVYASVA PSFIANYNGA GIEVLETGLK ALGFAGAEET AIGATHVKTA
YEQLLRDGQR DVLISSCCHS INLLIQKYYP DLLPYLADVA SPMQAHCLDI KRRHPDARTV
FIGPCLAKKD EADRYQGIVD AVLTFEELTE WFKAQGVALG TGHASREDSR ARLFPTTGGI
LKTMACDRPG YTYLALDGTE NCKAALEDIR HGNLHHCFIE MSACIGSCIG GPVMEKYHHT
PIRDFAAVSA YAGGKDFPIE SLPDGALKKR LAYLGKPQRM PGEQEIRDIL RQMGKTKPEH
ELNCGTCGYN TCREKAIAVY QGKADLSMCL PFLKDRAEHF SNSVLNNAPN GIIVLNDKLE
VQQINRAALS ILNLRSASDV LGEQVIRILD PQDFMQARDT GRSVRDRRTY LAEYGRYVDE
TIVYDREFHQ ILCILRDVTE QEQERERRES MREKTIETAD QVVDKQMRIV QEIASLLGET
AAETKIALAK LKESISDE
//
