ID   R5AX54_9FIRM            Unreviewed;       294 AA.
AC   R5AX54;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=HTH lysR-type domain-containing protein {ECO:0000259|PROSITE:PS50931};
GN   ORFNames=BN455_01754 {ECO:0000313|EMBL:CCX46504.1};
OS   Firmicutes bacterium CAG:103.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262999 {ECO:0000313|EMBL:CCX46504.1, ECO:0000313|Proteomes:UP000018290};
RN   [1] {ECO:0000313|EMBL:CCX46504.1, ECO:0000313|Proteomes:UP000018290}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:103 {ECO:0000313|Proteomes:UP000018290};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX46504.1}.
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DR   EMBL; CAWL010000177; CCX46504.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5AX54; -.
DR   Proteomes; UP000018290; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08414; PBP2_LTTR_aromatics_like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF17; LYSR FAMILY TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018290}.
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   294 AA;  32426 MW;  1EE34329F0A88036 CRC64;
     MSIQRLPVFL SAAEHLNFTR AAEEQCISQT AVSQQIKLLE QELGYALFVR GKRGVSLTPA
     GEVFYRQCRQ LMIRYNDAAA QGKKVALGNA TDLRIGYAGA YELWTIVSQI RKYHRQHPEA
     EIEFQLGSNQ SLLSGLAEGR LDMAVLSGFG VELGKGLDSR VTLSDPCMVM ISASHPLAAK
     KEIHPRELKG MPIVLNRAQD SQPSAGLIAD MYANMGLREN KRMYADDFYS IALIINTGIA
     FSIMPASVAC WGIDGVVFRP VQGFKAKART LLVYPRGSQD TGIRSFVSLI KPKR
//