ID   R5CGC5_9FIRM            Unreviewed;       465 AA.
AC   R5CGC5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=NADPH-dependent glutamate synthase GltA3 {ECO:0000313|EMBL:CCX65514.1};
GN   ORFNames=BN785_01930 {ECO:0000313|EMBL:CCX65514.1};
OS   Firmicutes bacterium CAG:791.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262993 {ECO:0000313|EMBL:CCX65514.1, ECO:0000313|Proteomes:UP000018038};
RN   [1] {ECO:0000313|EMBL:CCX65514.1, ECO:0000313|Proteomes:UP000018038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:791 {ECO:0000313|Proteomes:UP000018038};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCX65514.1}.
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DR   EMBL; CAWT010000143; CCX65514.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5CGC5; -.
DR   STRING; 1262993.BN785_01930; -.
DR   Proteomes; UP000018038; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006004; SudA-like.
DR   NCBIfam; TIGR01316; gltA; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018038}.
FT   DOMAIN          21..130
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          143..451
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   465 AA;  49989 MW;  A776BAD05633EFF7 CRC64;
     MAIQVDMMKK VPVREQDPKV RATNFEEVCL GYNKEEAEAE ATRCLNCKNP QCVQGCPVSI
     NIPGFISQLK EGNVRGAYEI ISESSALPAV CGRVCPQERQ CEAKCIRGIK GEAVSIGKLE
     RYTADTAKEL GIRPENHSVP NGKKVAVIGA GPSGLTCAGD LAKLGYEVRV FEALHKAGGV
     LVYGIPEFRL PKERVVAKEI ENVEALGVTI ETDCVVGHST TVQDLMDKEG FDAVFIGSGA
     GLPRFMNIPG EQALGVFSAN EFLTRSNLMG AYSEKSRTPI MRPKKCVVVG GGNVAMDAAR
     TALRLGAETH IVYRRGEEEL PARKEEVGHA KEEGIVFDLL CNPVEILVDE NGWVKGCRCI
     RMELGEPDAS GRRSPVEVPG SEFDIECDAV IMSLGTSPNP LLHRTTEGLE ADRRGRLIVK
     EGTEETTKKG VFAGGDAVTG AATVILAMGA GKQAAKEIDE YLKSV
//