ID R5E366_9BURK Unreviewed; 1381 AA.
AC R5E366;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:CCX85674.1};
GN ORFNames=BN548_01120 {ECO:0000313|EMBL:CCX85674.1};
OS Parasutterella excrementihominis CAG:233.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Parasutterella.
OX NCBI_TaxID=1263099 {ECO:0000313|EMBL:CCX85674.1, ECO:0000313|Proteomes:UP000018034};
RN [1] {ECO:0000313|EMBL:CCX85674.1, ECO:0000313|Proteomes:UP000018034}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:233 {ECO:0000313|Proteomes:UP000018034};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCX85674.1}.
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DR EMBL; CAXE010000038; CCX85674.1; -; Genomic_DNA.
DR Proteomes; UP000018034; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:CCX85674.1};
KW Hydrolase {ECO:0000313|EMBL:CCX85674.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 153..316
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 344..515
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1381 AA; 156726 MW; 53831ECCAD21E82F CRC64;
MAGDLRDLKA KLLEARKAEK KPQAVSQKQE PPRTKLTLKK KTPAASSGAS AASKSAEVKA
SAQKKNPAEP SKRPAPKGKG TSLKELSDLR VLRNQINAPQ EQKDINESKK PAASEKKPSR
ALVKVGNEVL RNIPPKLELQ ESLPVSERAD EIAEAIKNNQ VVIVSGETGS GKTTQLPKIA
MMVGRGQKGL IGHTQPRRIA ATSIAKRISE EMDAEVGQVA GYKIRFKDEL EPGATIKLMT
DGILLAETQR DRLLKAYDTI IIDEAHERSL NIDFLLGYLR EILPKRPDLK LIITSATIDS
ERFAKHFESV NKKPVPSINV SGRLYPVQIR YRPVQDEEEN DDRTLMQAIA DACDELMGAG
SGDILVFLPG EREIREAAEA LSPAARKGVE ILPLFSRLSI EEQDRIFKTD GRRRIVLATN
IAETSLTVPG IRYVVDTGLA RVKRYSYRNK VEQLQIEPIS QAAAKQRAGR CGRVANGICI
RLYDEKDFEK RSEFTDPEIL RSSLATVILR MKSLHLTDVR EFPFVQAPLQ RAITDGYDLL
IELNAVKERG GELTPVGKEL ARLPLDARLA RMLQAAAENQ ALAEVLIIAS AISIQDPRER
PLDAQDKAAA AHKKFADEKS DFLSLIKLWN WTQDAIANKE SNRLLEQKFR QNYLSVKRLR
EWRDVYRQLK ELTQEMGWRL NTAPATYEQL HKALLSGLLG NIGMKDVQAD YKTPPYIGAR
GIKFWPWPGS SLAKKGGKWI MASEIVETTR LFARTLANLE PEWIEKVGSH LIKKSWSDPH
WEKKAGNVIA LEKGTLYGLP VYTERKVDFS RKDPKTSREI FIRRALVEEE LESQAPFWQH
NVAMINNIRE MEHKSRRPDV LVDDSMIYEF YDKKISQGVV NQQTFDKWRE KAEAENPKLL
FLQKSDLMRH DAAGITIEYF PKKLEIAGIP MALNYNFDPG SPRDGVTMTV PLYALNQLDP
VRLEWLVPGM VKEKVQMLLK SLPQRLRRHF VPLPDWAKSF AQRHEVPDGD LIELLIKEAR
EQFRIDIQKS DFKFEMLPPH LSMNYKVVDE HGRQLAMSRS IPQLRSELST EARKTFQNIA
SQDSKVAEDL QDEITEWNFG ELPDVMEIKK KGISLIGHPA LVDKGEYCSL EVFDDPDQAA
RIHRRGLIRL IRLGLKEQIK YLDKNLKSMQ TTQIQGASIV SLRKAFPSFE ELKQDVIDAS
IETAAFTGEL PVNEEQFRET IANVKEKLGL LTLELARLLS SIVSEAALAQ QKLNSIKSYK
EVSEDITAQL SDLFPPHFLL TIPFSQLRHY PRYMKAIQVR IDRLKNDPGR DAERMAEIRQ
LTVNYKRELS ARRGVYDAKL VEFGNMLQEL RVSLFAQELR TPMPVSVKRL NKMWDAILRE
H
//
