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Database: UniProt
Entry: R5F7D0_9CLOT
LinkDB: R5F7D0_9CLOT
Original site: R5F7D0_9CLOT 
ID   R5F7D0_9CLOT            Unreviewed;       415 AA.
AC   R5F7D0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   25-OCT-2017, entry version 20.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCY00793.1};
GN   ORFNames=BN723_00987 {ECO:0000313|EMBL:CCY00793.1};
OS   Clostridium bolteae CAG:59.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium; environmental samples.
OX   NCBI_TaxID=1263064 {ECO:0000313|EMBL:CCY00793.1, ECO:0000313|Proteomes:UP000017941};
RN   [1] {ECO:0000313|EMBL:CCY00793.1, ECO:0000313|Proteomes:UP000017941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:59 {ECO:0000313|Proteomes:UP000017941};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000106-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000106-3};
CC       Note=Divalent metal cations. Prefers magnesium or manganese.
CC       {ECO:0000256|PIRSR:PIRSR000106-3};
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCY00793.1}.
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DR   EMBL; CAXJ010000289; CCY00793.1; -; Genomic_DNA.
DR   Proteomes; UP000017941; Unassembled WGS sequence.
DR   GO; GO:0004471; F:malate dehydrogenase (decarboxylating) (NAD+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.50.10380; -; 1.
DR   InterPro; IPR015884; Malic_enzyme_CS.
DR   InterPro; IPR012301; Malic_N_dom.
DR   InterPro; IPR037062; Malic_N_dom_sf.
DR   InterPro; IPR012302; Malic_NAD-bd.
DR   InterPro; IPR001891; Malic_OxRdtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00390; malic; 1.
DR   Pfam; PF03949; Malic_M; 1.
DR   PIRSF; PIRSF000106; ME; 1.
DR   SMART; SM01274; malic; 1.
DR   SMART; SM00919; Malic_M; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00331; MALIC_ENZYMES; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000017941};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000106-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017941}.
FT   DOMAIN       15    148       malic. {ECO:0000259|SMART:SM01274}.
FT   DOMAIN      160    383       Malic_M. {ECO:0000259|SMART:SM00919}.
FT   ACT_SITE     36     36       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR000106-1}.
FT   ACT_SITE     91     91       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000106-1}.
FT   METAL       133    133       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000106-3}.
FT   METAL       134    134       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000106-3}.
FT   METAL       159    159       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000106-3}.
SQ   SEQUENCE   415 AA;  44007 MW;  AF2DCB4C4B92D3F2 CRC64;
     MDYAEAALKM HRENHGKLEM ASKIPLTTRD ELSTAYTPGV AAPCLKIKED KSEAYTYTAK
     GNLVAVVTDG TAVLGLGDIG PEAAMPVMEG KAVLFKKFGG VDAVPICLDT RDTEEIIETV
     KRIAPTFGGI NLEDISAPRC FEIEQRLERE LDIPVFHDDQ HGTAIVATAA LINALKLTGK
     QMDGIKVIVN GPGSAGTAIT EMLLGAGVKD LIVCDEHGAL CPGREKMDGH KEKLSLMTNV
     GKEKGRLEDV IAGADVFIGV SAAGVVSKDM VRTMKKDAIV FAMANPVPEI MYEEAKEAGA
     RVMATGRSDC PNQINNVLVF PGLFRGALDC RARDITCGMK LAAAYGIAGL VSGEELGEEY
     IIPSAFDERV AKAVAEAVKR AAVKRDAAKR NAVKPAALKA AGEVKAAGEV KQGRE
//
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