ID R5FLG3_9FIRM Unreviewed; 639 AA.
AC R5FLG3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=NADH dehydrogenase (Quinone) {ECO:0000313|EMBL:CCY04474.1};
GN ORFNames=BN468_00937 {ECO:0000313|EMBL:CCY04474.1};
OS Faecalibacterium sp. CAG:1138.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=1262896 {ECO:0000313|EMBL:CCY04474.1, ECO:0000313|Proteomes:UP000018132};
RN [1] {ECO:0000313|EMBL:CCY04474.1, ECO:0000313|Proteomes:UP000018132}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:1138 {ECO:0000313|Proteomes:UP000018132};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY04474.1}.
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DR EMBL; CAXL010000039; CCY04474.1; -; Genomic_DNA.
DR AlphaFoldDB; R5FLG3; -.
DR STRING; 1262896.BN468_00937; -.
DR Proteomes; UP000018132; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000018132};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 582..611
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 612..639
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 639 AA; 69513 MW; 0585B3CA00ACB8E3 CRC64;
MLKTRQDLKE FRDACVAAAK LQKRRILVCA GTGCVSSGSL KIFDRLKELI EESGIKCSVE
LKVEPHDPGL HGKECDSCAE KGESIAMKKS GCHGFCEMGP LVRIEPEGYL YTKVRLSDCE
EIVEKTVLQN EPIDRLAYKV NGEIYRKQEE IPFYKKQDRI VLEHCGHIDA LSVKEYLSIG
GYTAFEKALF DMTPEDVVNE ISESKLRGRG GGGFPVGKKW AQVAKQKNFP KYVVCNGDEG
DPGAFMDRSV MEGDPHRMLE GMMIAAVACG ANEGYIYVRA EYPLAVFRLR TAIEQAREIG
LLGKNILGSG FDFDLHINQG AGAFVCGEGS ALTASIEGKR GMPRTKPPRT VEHGLFDKPT
VLNNVETYAN VPSVITKGAK WFCTIGTETS PGTKAFALTG NIANTGLIEV PMGTTLKDVI
FEIGGGIRNG GKFKAVQIGG PSGGCLTSEH LDLALDFDSL KKVGAIIGSG GMVVMDESSC
MVEVARFFMD FTQRESCGKC VPCREGTKRM LEILDRIVDG KGKEGDIELL LDLADTISNT
ALCGLGKTAA GPVVSTIKYF RDEYEAHIRE KRCPAGKCQK LKRYVIDPSV CKGCSKCARN
CPVGAISGEI KKPFVIDQNK CIKCGSCVSN CNFKAIREG
//
