ID R5GNJ5_9FIRM Unreviewed; 996 AA.
AC R5GNJ5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=DNA/RNA helicase DEAD/DEAH box family {ECO:0000313|EMBL:CCY14126.1};
GN ORFNames=BN498_01976 {ECO:0000313|EMBL:CCY14126.1};
OS Eubacterium sp. CAG:146.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262879 {ECO:0000313|EMBL:CCY14126.1, ECO:0000313|Proteomes:UP000018404};
RN [1] {ECO:0000313|EMBL:CCY14126.1, ECO:0000313|Proteomes:UP000018404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:146 {ECO:0000313|Proteomes:UP000018404};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY14126.1}.
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DR EMBL; CAXQ010000180; CCY14126.1; -; Genomic_DNA.
DR AlphaFoldDB; R5GNJ5; -.
DR Proteomes; UP000018404; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd09204; PLDc_N_DEXD_b2; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR021835; DUF3427.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF11907; DUF3427; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CCY14126.1};
KW Helicase {ECO:0000313|EMBL:CCY14126.1};
KW Hydrolase {ECO:0000313|EMBL:CCY14126.1};
KW Nucleotide-binding {ECO:0000313|EMBL:CCY14126.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018404}.
FT DOMAIN 239..390
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 446..611
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 996 AA; 114884 MW; 7B802CF616EDE847 CRC64;
MDANVIRELQ NGLNAAYING SVAVNLAYKP AFVSNNPEEG KKVISSVEDE LLRCDQFQIS
VAFITMGGVT PLLQTLKELE EKGVKGQILT TNYLNFSEPR ALEKLNGLKN ITLKMYDVEA
AGNGFHTKGY IFKKEEIYRI IIGSSNMTSA ALAINKEWNT KLISTENGEV AEEIVEEFHN
LWNSEYALPY DDFYEVYRER YNIIKHQREI AKSEEIPSLE KYRLKPNSMQ ERFIANLRKI
LEQGEERALL ISATGTGKTF ASAFAMRELG FKRVLFLVHR GQLARQTKKS YEKVFAKSIS
MGLVGAGYHE YDADYVFATV QTLNRDEHLL QYEKDAFDCI VLDEAHHVSA ETYQKIMRHF
TPKLWLGMTA TPDKRDDNIA GRNVYEIFNY QIAYEIRLQQ AMEEDLLCPF HYFGITDLSI
IGDNEECNRD FSMLTSDERV KHIVTQADYY GYSGEKIKGL IFCSTLKETE ELSAKFNQMI
NPSTGKVFRT IALNGSASEQ ERQTAFERLA MDESDATEEN EPLDYIFSVE ILNEGVDIVE
VNQVIMLRPT QSPIVFIQQL GRGLRKANGK EYVVILDFIG NYNNNFMIPI ALSGDRTYNK
DNIRRYIMEG GRVIPSASTV HFDEVSRKRI FSSVDNANFS DIKLIKENYM NLRNKLGRIP
KLCDFDAYGE MDVLRIFDNK SLGSYYKFLV KYEKDYKIRL SEQEEKVIEF VSKKLANGKR
IQELQLLKRM LTYVKGTAQI GLFSGLSEDM KHYGKEISQN QKKNIVNIMT NEFPAGTGKK
AYSQCVFIEE DGNDYKPTKS FAEMAMHEEF YSILNELVDF GIGRYKRDYQ SSYEDTDLVL
YQKYTYEDVC RLLNWEQNEV PLNIGGYKYD KKTKTFPVFI NYDKPANISD TTKYEDHFVK
GFRDRLIAIS KSGRSLKSED VQNFLKAKER NIKVELFVRK NKDDKISKEF YYLGHMTASG
NTKEFTMANT EKTAVEIEWI LDVPVREDIY EYIVNA
//
