ID   R5J331_9CLOT            Unreviewed;       582 AA.
AC   R5J331;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=HAMP domain-containing protein {ECO:0000259|PROSITE:PS50885};
GN   ORFNames=BN757_02716 {ECO:0000313|EMBL:CCY43451.1};
OS   Clostridium sp. CAG:7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262832 {ECO:0000313|EMBL:CCY43451.1, ECO:0000313|Proteomes:UP000018268};
RN   [1] {ECO:0000313|EMBL:CCY43451.1, ECO:0000313|Proteomes:UP000018268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:7 {ECO:0000313|Proteomes:UP000018268};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY43451.1}.
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DR   EMBL; CAYE010000129; CCY43451.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5J331; -.
DR   STRING; 1262832.BN757_02716; -.
DR   Proteomes; UP000018268; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018268};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          302..348
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   COILED          333..363
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   582 AA;  66208 MW;  0F8AF51528FF676A CRC64;
     MKRERYFRDE LWRMFAIYAI LPAALFTFFC GILFMAVLLH GRERANRDYL AYVTGRVKQT
     VESCEQGIET LAELPQAVSG PGYVLERNRI FQIFYGISEQ AGYEPELYLV DQRGRLLLSN
     KEKLPSYLNK RQEVEWGIYA AMDARPGQTA FRLMNGWDSG ASTAVFGRWV GSEDGNGRYI
     ILAVPGSGLL RTLARSGEQV AVTDRYGWAY FCNNGLFLTD SNQVRPAVKE AGAYMRLDQK
     TYFTSENNLE NGRFHIYVMS DVQNVLTSLV FAGILVAVAL LLMTAWVLFQ SKQVTERKTE
     DLYKLLDGME LARQGNLERT GAIDRDNEFK MIAEAYNETI TSLKEQMENN QKMTELLALA
     QTKQLESQFN PHFLYNTLEN IRYMCKLEPA TAERMVFSLS KLLRYSLDGS REQVTLEEDL
     GHLNNYLSIL EMRFGSRFEY KIDIAPECMQ CLIPKLVLQP MIENSVKYGF GNQLNLHVEL
     KAYIHEEKLM MICRDDGVGM SAAMVEKLCA LMNQKEAPGR HSGLYNIHRR IQLLYGYPYG
     VEIRSLEGHG TTLVVTLPAV AEKNVHSVQG DNNDASGNDS GR
//