GenomeNet

Database: UniProt
Entry: R5JEM1_9FIRM
LinkDB: R5JEM1_9FIRM
Original site: R5JEM1_9FIRM 
ID   R5JEM1_9FIRM            Unreviewed;       252 AA.
AC   R5JEM1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000256|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000256|HAMAP-Rule:MF_01805};
GN   ORFNames=BN781_00098 {ECO:0000313|EMBL:CCY52820.1};
OS   Coprococcus sp. CAG:782.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Coprococcus.
OX   NCBI_TaxID=1262863 {ECO:0000313|EMBL:CCY52820.1, ECO:0000313|Proteomes:UP000018002};
RN   [1] {ECO:0000313|EMBL:CCY52820.1, ECO:0000313|Proteomes:UP000018002}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:782 {ECO:0000313|Proteomes:UP000018002};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000256|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000256|HAMAP-
CC       Rule:MF_01805}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY52820.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAYJ010000002; CCY52820.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5JEM1; -.
DR   STRING; 1262863.BN781_00098; -.
DR   Proteomes; UP000018002; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 6.10.250.2410; -; 1.
DR   Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR   PANTHER; PTHR33969:SF2; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|HAMAP-Rule:MF_01805};
KW   Cell division {ECO:0000256|HAMAP-Rule:MF_01805};
KW   Chromosome partition {ECO:0000256|ARBA:ARBA00022829, ECO:0000256|HAMAP-
KW   Rule:MF_01805}; Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018002}.
SQ   SEQUENCE   252 AA;  29267 MW;  27C082CF61F27D86 CRC64;
     MAALDVKLNV FEGPLDLLLH LIEKNKVQIF DIPIVTITDQ YIEYINNMEE EDLDVMSEFL
     VMAATLIRIK SKMLLPKDEE VSEEEEDPRD ELVRRLLEYK MYKYAACELK DMELDGEKNL
     YKGASIPAEV KNYHEEIDPY ELVSGLGLDL EKLNEIFKSV MRKQVDKLDP VRSKFKTIEK
     EEISLEDKMA EVREQVRGLN GINFRTLLEM QPSKMNVIVT FLAILELMKI SAITIRQDEL
     FGDIIIDSKD EL
//
DBGET integrated database retrieval system