ID R5JGJ8_9FIRM Unreviewed; 411 AA.
AC R5JGJ8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:CCY47917.1};
GN ORFNames=BN738_00187 {ECO:0000313|EMBL:CCY47917.1};
OS Peptostreptococcus anaerobius CAG:621.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Peptostreptococcus.
OX NCBI_TaxID=1263100 {ECO:0000313|EMBL:CCY47917.1, ECO:0000313|Proteomes:UP000018261};
RN [1] {ECO:0000313|EMBL:CCY47917.1, ECO:0000313|Proteomes:UP000018261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:621 {ECO:0000313|Proteomes:UP000018261};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY47917.1}.
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DR EMBL; CAYH010000046; CCY47917.1; -; Genomic_DNA.
DR AlphaFoldDB; R5JGJ8; -.
DR Proteomes; UP000018261; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21109; SPASM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018261};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 89..317
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 411 AA; 47408 MW; 4B14F3AA740068D4 CRC64;
MKKYFAKELA RYNYSGNLAF LSNKFTGEWI KIPKEIMDIL LYSYSKKMST YESYELIEGN
DNKEYLESVY YFLDKMGLLA PVPAYKRDLK YIPLVTISIT NNCNLSCSYC CTKSSNKKQY
LDLILKDIKK AIDFAIRLNP EGLKISGGEP MLRKDFFEIL AYARENYSGK IILATNATLI
TLNNIDKLTS QIDSIEISLD SYDNKTFSLV RGCTNKKYDD IKEIINELKQ RGLNNIHASI
VVGKNNAMYL HKFRAECENM GVKPVVRNFM STGDINVDKL YLNNMNEFEY NGCSTEGTTK
EAMVCNAGVN QIFIDYDGKI YPCPLLNDEI FMISSLDDIN ENIIDSILNN SYHILKVIDQ
IRPNNNLRCR QCDEALFCQN CIYKITQMLE NEEVFNFNCK NANKMNIEER L
//
