ID R5L3W2_9CLOT Unreviewed; 498 AA.
AC R5L3W2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:CCY67971.1};
GN ORFNames=BN753_01600 {ECO:0000313|EMBL:CCY67971.1};
OS Clostridium sp. CAG:678.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262831 {ECO:0000313|EMBL:CCY67971.1, ECO:0000313|Proteomes:UP000017959};
RN [1] {ECO:0000313|EMBL:CCY67971.1, ECO:0000313|Proteomes:UP000017959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:678 {ECO:0000313|Proteomes:UP000017959};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCY67971.1}.
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DR EMBL; CAYP010000062; CCY67971.1; -; Genomic_DNA.
DR AlphaFoldDB; R5L3W2; -.
DR STRING; 1262831.BN753_01600; -.
DR Proteomes; UP000017959; Unassembled WGS sequence.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000017959}.
FT DOMAIN 3..79
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 105..333
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 113
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 498 AA; 54608 MW; 6AB32ED68D5D7690 CRC64;
MLYTSTRDNS VKVSAAHAIA QGISEEGGLF VPCEFPHFSV DKIKEMASMC YIDRAKTVLR
EFLDDFSEEE LDYCVSGAYA AGKFSSDAVA PTVNIHGNEN VLELWHGPTC AFKDMALQLL
PYLMTVSAKK TADGKTIVIL VATSGDTGKA ALEGFKDVDH TKILVFYPEN GVSPMQKLQM
VTQEGSNVSV CAVKGNFDDA QSAVKAIFTN DEIKEKLAQK NMMFSSANSI NWGRLVPQIV
YYFSAYCDLL NSGSIHAGDE MNVVVPTGNF GNILACYYAK RMGLPVKKLV CASNSNNVLT
DFLTTGTYDK NRAFYTTTSP SMDILISSNL ERLLYHLSGN DDALINDLMR RLSENGVYTV
SESLLAEIQK HFSAGFAEES EVNETIKAYF DQFGYLCDTH TAVALKVYGD YVKNTGDDIP
TVIDSTASPY KFSRSVLSAV TGGNLPDADE FEMVNELYKT TGSAVPAPLV SLKDKEVRFD
HVCTKEDMGE MVFKLLGI
//
