GenomeNet

Database: UniProt
Entry: R5LKS5_9FIRM
LinkDB: R5LKS5_9FIRM
Original site: R5LKS5_9FIRM 
ID   R5LKS5_9FIRM            Unreviewed;       250 AA.
AC   R5LKS5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=Segregation and condensation protein A {ECO:0000256|HAMAP-Rule:MF_01805};
GN   Name=scpA {ECO:0000256|HAMAP-Rule:MF_01805};
GN   ORFNames=BN569_01091 {ECO:0000313|EMBL:CCY78019.1};
OS   Butyrivibrio crossotus CAG:259.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Butyrivibrio.
OX   NCBI_TaxID=1263062 {ECO:0000313|EMBL:CCY78019.1, ECO:0000313|Proteomes:UP000018300};
RN   [1] {ECO:0000313|EMBL:CCY78019.1, ECO:0000313|Proteomes:UP000018300}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:259 {ECO:0000313|Proteomes:UP000018300};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in chromosomal partition during cell division.
CC       May act via the formation of a condensin-like complex containing Smc
CC       and ScpB that pull DNA away from mid-cell into both cell halves.
CC       {ECO:0000256|HAMAP-Rule:MF_01805}.
CC   -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC       the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC       Smc. The presence of the three proteins is required for the association
CC       of the complex with DNA. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805}.
CC       Note=Associated with two foci at the outer edges of the nucleoid region
CC       in young cells, and at four foci within both cell halves in older
CC       cells. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC   -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000256|HAMAP-
CC       Rule:MF_01805}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY78019.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAYU010000082; CCY78019.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5LKS5; -.
DR   Proteomes; UP000018300; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 6.10.250.2410; -; 1.
DR   Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR   HAMAP; MF_01805; ScpA; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR   PANTHER; PTHR33969:SF2; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|HAMAP-Rule:MF_01805};
KW   Cell division {ECO:0000256|HAMAP-Rule:MF_01805};
KW   Chromosome partition {ECO:0000256|ARBA:ARBA00022829, ECO:0000256|HAMAP-
KW   Rule:MF_01805}; Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018300}.
SQ   SEQUENCE   250 AA;  29282 MW;  4C5F3B88EDDBC3B3 CRC64;
     MALEVKLEVF EGPLDLLLHL IDKNKVNIYD IPIVLITDQY IEYIDNMEKS DLNLVSEFLV
     MAAMLLDIKS KMLLPKDPDV AEDDNSDPRQ DLVEKLLEYK MYKYMSYELK DRQIEAENSF
     YKAPDIPEEI LSYVPPVDTR ELMTGITLQR LREIFNEVIR RQENKVDPIR SKFGKIEKEE
     VNMEEKMEFV HSYIKTHKTF LFRQLLSESK SRTQVIVTFL VILELIKGGK ISVTQENRTD
     DILINSLEVG
//
DBGET integrated database retrieval system