ID   R5MIZ1_9CLOT            Unreviewed;       539 AA.
AC   R5MIZ1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Orn/Lys/Arg decarboxylase major domain protein {ECO:0000313|EMBL:CCY85256.1};
GN   ORFNames=BN500_02094 {ECO:0000313|EMBL:CCY85256.1};
OS   Clostridium sp. CAG:149.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262776 {ECO:0000313|EMBL:CCY85256.1, ECO:0000313|Proteomes:UP000017912};
RN   [1] {ECO:0000313|EMBL:CCY85256.1, ECO:0000313|Proteomes:UP000017912}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:149 {ECO:0000313|Proteomes:UP000017912};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY85256.1}.
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DR   EMBL; CAYX010000238; CCY85256.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5MIZ1; -.
DR   Proteomes; UP000017912; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017912}.
FT   DOMAIN          4..306
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|Pfam:PF01276"
FT   DOMAIN          452..499
FT                   /note="Orn/Lys/Arg decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03711"
FT   REGION          412..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  60947 MW;  F7FFFA0DBE5EA77B CRC64;
     MRLIDRLEEY GRSDFYGFHM PGHKRRQELG ITSFPNPFSV DITEIEGFDN LHHAEGILRD
     SMEQAAQIYG SDRTYYLVNG STCGILAAIS AAVPEGGTLL MARNSHKSAY HGVMLRGLKA
     LYVYPEIFEE YGIQGGISAE EIDRILKEQG KREIGAVFLT SPTYEGIVSD VERIAETVHS
     YGLPLIVDQA HGAHLAFGEG TGKGRREGRL FARSALELGA DVVIESVHKT LPSLTQTALL
     HIRGSRIDRE CLEFYLRVYQ SSSPSYLLMA SIDNCIQYMD LEGRKHLEKY GRRLEQWMER
     AEEWKCLWIL DDSVIGRKAA ADRDLSKLVV GIRPHVRREL GEKTAEENGG RERYNGTWLA
     AEVRERFHLE PEMCCDRYVI FMTSLMDSEE GLLRLMEALC TIDRELCEKA AEENKREGTE
     ESKREDEKGA ELAAQDSRLF TWTRDTEVRM NMSEAIRRPG RRIRLEQAAG LVSRGFLTVY
     PPGVPAIVPG EEISREALQM ILSNRRLGLT VEGIYEDGTV DTAVREAVEK NGKEGQMER
//