ID   R5MN22_9BACE            Unreviewed;       449 AA.
AC   R5MN22;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Alpha-L-fucosidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN461_00758 {ECO:0000313|EMBL:CCY93145.1};
OS   Bacteroides sp. CAG:1076.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262735 {ECO:0000313|EMBL:CCY93145.1, ECO:0000313|Proteomes:UP000018060};
RN   [1] {ECO:0000313|EMBL:CCY93145.1, ECO:0000313|Proteomes:UP000018060}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:1076 {ECO:0000313|Proteomes:UP000018060};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY93145.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAZB010000165; CCY93145.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5MN22; -.
DR   Proteomes; UP000018060; Unassembled WGS sequence.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   SITE            267
FT                   /note="May be important for catalysis"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ   SEQUENCE   449 AA;  51761 MW;  88B8B3731AF23AB2 CRC64;
     MIKKQIVALF TAFCCATAPV IGQTQEKEQQ DAQKEKRMEW FANAKLGIFI HWGIYSVKGV
     SESWSFFNKY LPYEEYMSQK DGFTASKYDP KAWVDLIKES GARYTVITTK HHDGMALWDT
     KAGELSTVKC TPAKRDLISP FVKEVRKQGL KLGFYYSLLD WSHPDYPNKT RTEVRYKNDS
     VRWKRFVDFN MAQLSELNKT WKPDLYWFDG DWEQTAEAWN SKGIVELLRS DNKNVIINSR
     IQGYGDYATP EQGVPIVRPE DKYWELCMTM NDSWGYQHTD TNYKSPFILL RTFVDCLSMG
     GNLLLDIGPK EDGTIPEEQV AILKEFGRWT KKHKEAIYDT RAGIPTEHFQ GYTTLNKAGD
     ILYLYLPYKP NGPIEVKGLM NKVNRVWVVG NGSMLSYKVY NKNYWSEVPG NLYIDVPEHV
     LDPQITVIAV LLDGPVKLYR GAGQVIESN
//