ID   R5MVI8_9FIRM            Unreviewed;       785 AA.
AC   R5MVI8;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Helicase conserved C-terminal domain protein {ECO:0000313|EMBL:CCY93704.1};
GN   ORFNames=BN804_00353 {ECO:0000313|EMBL:CCY93704.1};
OS   Firmicutes bacterium CAG:884.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1262990 {ECO:0000313|EMBL:CCY93704.1, ECO:0000313|Proteomes:UP000018073};
RN   [1] {ECO:0000313|EMBL:CCY93704.1, ECO:0000313|Proteomes:UP000018073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:884 {ECO:0000313|Proteomes:UP000018073};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|ARBA:ARBA00008708}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY93704.1}.
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DR   EMBL; CAZD010000017; CCY93704.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5MVI8; -.
DR   STRING; 1262990.BN804_00353; -.
DR   Proteomes; UP000018073; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCY93704.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018073}.
FT   DOMAIN          103..273
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          311..499
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   785 AA;  91660 MW;  475A9889D4D37027 CRC64;
     MGLTRIDVLK KINTYSMTNN KMGLIQILCE IIENKEFLLN NLDIVQIAIE IGELYGYNEY
     LKKYKEKLEI TDIDSTNSIL RKTMFTSLYD KNVVFNSGQL SLLEEIKNNK RIFISAPTSF
     GKTSLIFEHI YLNYKSYDNI CIIVPTNSLE EELFYKFLLF NKKTNNKYKI LTSPHKNKGN
     SIYILTPEKY LLLNEGDDIK FNLIVIDESY KIEDSEDEIK YNSDDILNTR SSKYRMVFEL
     CGASDSKLIF LSPYTYNKSE SMLEFFNKYN VTFVDRTYNY VGHQIEDVST QTKAQKLFNT
     TNISYKSDAA GIIKAVSILP YLNDSTIIYI MYPAELKKIL PLINNDITEC INANDRFKKF
     YEHLVNNYTF DNSNWYVLEA LKKGVGLYIS PIPRYIKREM LNLFNDGFLK ILVVTTAFAE
     GVNSSAKNII ITNEIVGANK KMTNLDMLNL SGRAGRFGKY SKGYIYAVKN TISERLKEAE
     KNGVTIANSN YEFPKNNNLR SDYEIDIIDE KWLTKEEIDI KKETDKIMIE YGLTDEDLRI
     SLCTSRNTKL ILYKYFCKTN KKEQNDERYQ VIKNLLASDR NDVIKSLEYV FKEIKAAGIS
     IYSDKGDIQA YSKNEKFLWG IFYAIHSSGN IKDILKKRKE YIWNEYNSVI SKDIYFSSKN
     IEKILELYGK KWISEFISDG KIDDFKLYNN AFKFISSIIE YRIPFYIGLY VSIFKLFSKK
     NTLDYLFDFD IVDISTSLEN KNVDEKYSNM IEYGLPLDMV KKIINDEMLD DFENLILSDY
     KSIYE
//