ID   R5N355_9FIRM            Unreviewed;       329 AA.
AC   R5N355;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Transketolase domain protein {ECO:0000313|EMBL:CCY91617.1};
GN   ORFNames=BN519_01042 {ECO:0000313|EMBL:CCY91617.1};
OS   Eubacterium sp. CAG:180.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1262882 {ECO:0000313|EMBL:CCY91617.1, ECO:0000313|Proteomes:UP000018411};
RN   [1] {ECO:0000313|EMBL:CCY91617.1, ECO:0000313|Proteomes:UP000018411}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:180 {ECO:0000313|Proteomes:UP000018411};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCY91617.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAZC010000050; CCY91617.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5N355; -.
DR   STRING; 1262882.BN519_01042; -.
DR   Proteomes; UP000018411; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR43825:SF5; HYPOTHETICAL TRANSKETOLASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018411}.
FT   DOMAIN          23..187
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   329 AA;  35854 MW;  80C1D2E37042C683 CRC64;
     MNKTVKTFEG ELELGHLDML VAASARDMWV EELQELAETD ERIVFVTADG GYAGKENEFR
     LKHPDRMLPV GIAEMDQVGI ASGLALCGKI PYINGFGPFL ALRTLDQVHT NVCYPNLPVR
     IVNTHSGLTS ASGPTHYNIM DIAIMRTLPN MTYVIPADAN QCVKLISKSV DYPGPMCIRI
     ARGAEPLVYT EDYDYEIGKA IIAHEGNDVT VVACGCTVAF AVSAANALEK EGIGVRVLDM
     HTVRPLDKQA IRDAIKDTGK IITAEDAFVI NGLGSAVSDL MADEGLQAKF KRLGIPNDEF
     PPLGDSYELY AHLGYDPEGI KKAIREILE
//