ID R5NY24_9BACT Unreviewed; 1116 AA.
AC R5NY24;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Helicase protein {ECO:0000313|EMBL:CCZ01752.1};
GN ORFNames=BN471_00444 {ECO:0000313|EMBL:CCZ01752.1};
OS Paraprevotella clara CAG:116.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Paraprevotella.
OX NCBI_TaxID=1263095 {ECO:0000313|EMBL:CCZ01752.1, ECO:0000313|Proteomes:UP000017958};
RN [1] {ECO:0000313|EMBL:CCZ01752.1, ECO:0000313|Proteomes:UP000017958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:116 {ECO:0000313|Proteomes:UP000017958};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ01752.1}.
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DR EMBL; CAZH010000082; CCZ01752.1; -; Genomic_DNA.
DR AlphaFoldDB; R5NY24; -.
DR Proteomes; UP000017958; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0006304; P:DNA modification; IEA:InterPro.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.90.1570.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013670; EcoEI_R_C_dom.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF08463; EcoEI_R_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CCZ01752.1};
KW Helicase {ECO:0000313|EMBL:CCZ01752.1};
KW Hydrolase {ECO:0000313|EMBL:CCZ01752.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000313|EMBL:CCZ01752.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017958};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 359..514
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 153..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1116 AA; 126827 MW; A309D486853B061E CRC64;
MRNFDIIKDI DGLETIHRYC AIAEDFQATN PMISVQQARL ALETMVKTVY RLKGWQIGER
ASLLSLTADE RFTAFVNSED LMKRIHYVRK IGNNAAHAND GFVGRRESFF AVLNLYYIVG
SIMLAWQVID TLPDFDKELV PQSAKTSTLT VVPQPDQAQA ATTQSADALA RAVGESSDAQ
PATVEARPVV NDLSEAETRK LYIDLLLHEA GWTVTEQVGK IVPRQAGIEI EVQGMPNESG
MGYADYVLFD ADGTPLAVVE AKRTNVDAVA GRHQAELYAD CLAARYVCPR PVIYYTNGFE
TNIIDGIGYP SRKVMGFHTI DELRRMIAQR GRTDITDLQI SDRITNRNYQ KRMIESVCKH
YNSKHRRALL VMATGTGKTR VSISLVDVLV RNNWVKNVLF LADRIELVNQ AKRNYAKLLP
NMTVSSLRDS DVDISARILF STYQTMIGHL DKDAKTFSLG RFDLIIIDEA HRSVFGKYGA
IFEYFDGLLL GLTATPRDEV DRFTYDLFGM EQGEPTDSYE YDEAVADGYL KPFRAIKDNS
KILTEGIDPD QLTPEEREQL DEIFEYEKMK AGLEPGDPYS RIINATEIFK YIYNHDTVDY
VLNRLMNDGI RVKDDTLIGK TIIFAYNHKH AVLIAERFAV LYPDLGPDFC RVIDDKEKYS
SDLIDKFADV ERLPQIAVSV DMLDTGIDVP EIVNLVFFKP IHSKIKFWQM IGRGTRLCEN
LFGEGKDKEE FLIFDFYRNF EYFEMNPEGA KPAKSQSIVS LLFNLRTDIK FALQDGTHQS
KEESKAFHDN LADILHQQIA NLNRNRIDVR LQLKAVETYA TPEAMVCLTL GDVMAMKGNI
SPLFKNAITD ISALKFDALV LKSQLALVDE TVNSTSSERK IMDIAGCLKE KKASIPQVMA
KMDVLNEVLS ARFWESKSLG SLERIRLELR DLIQYMDGGT GGQTFIINVT DTFEEDNSGV
NVTPIRTYRR RVEDYLKEHL SDDDTLQKIY HLEPLSGQDI TRLELIFWEE LGSKAEFEAQ
TRTKPYQRNV AAFIRSIIGV EQEVALEKYR ALIHGAELTR MQEEYLRMLI RYVCENGDIA
TVVLQQPPFN KFPVIFRDSR ESLIDYVKLI SQVIAV
//
