ID   R5Q6E7_9PROT            Unreviewed;       577 AA.
AC   R5Q6E7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Cell division protein FtsI/penicillin-binding protein 2 {ECO:0000313|EMBL:CCZ21879.1};
GN   ORFNames=BN820_00643 {ECO:0000313|EMBL:CCZ21879.1};
OS   Acetobacter sp. CAG:977.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acetobacter.
OX   NCBI_TaxID=1262685 {ECO:0000313|EMBL:CCZ21879.1, ECO:0000313|Proteomes:UP000018259};
RN   [1] {ECO:0000313|EMBL:CCZ21879.1, ECO:0000313|Proteomes:UP000018259}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:977 {ECO:0000313|Proteomes:UP000018259};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ21879.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAZQ010000057; CCZ21879.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5Q6E7; -.
DR   STRING; 1262685.BN820_00643; -.
DR   Proteomes; UP000018259; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Cell cycle {ECO:0000313|EMBL:CCZ21879.1};
KW   Cell division {ECO:0000313|EMBL:CCZ21879.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018259};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          86..194
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          248..526
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   577 AA;  63271 MW;  34A816A277ED51D3 CRC64;
     MFRFLKKSGT FYYPGQEIPL PEMMTAADKN SFSSLESGKN RLLFTAGVFL VSFGILCFRL
     FNVALNGEII EEARRAPVGV HALNIKMKRA DITDRNGVIL ATSLPSADLY AEVDKIKNPE
     MIAAALVQTL PDLKYKPLLK KLKSGRNFVY IKRALTPKEQ YEVNRLGFPA LNFQHVESRV
     YPQGALFAHI VGATDIDGKG IAGVEKAFNE RLSVQKEPVR LSLDAGIQDT VRLALKESVE
     KFNAEGAAAV LMNAKTGEVV ALVSLPDFDP NNLRQAKRKS LFNAATLGVY EVGSIMKLFN
     AAIGLETGKV KVSDTFDAAN PIILANYKIQ DEPKLRRVLS LPEILIHSSN VGAARIALNV
     GAEKQQEYLR RFGFFQPASL EIPERGHPLY PSKWREVNTA TAGYGYGVAV TPLHIAAATS
     ALVNGGVYHA PSLLFKRNTN EIIGERVISE KTSKIMRAIM RLVVTEGSGR RANVPGYEVG
     GKTGSAQKIA KGKYVKNSLR TSFVSAFPMD NPQYVLMVMM EAPQRIKETF NFNTAAWNAV
     PTAERIISAV APQLGITPRP YEPTQPAPYV KAALNAK
//