ID R5QCG2_9FIRM Unreviewed; 629 AA.
AC R5QCG2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA methylase N-4/N-6 domain-containing protein {ECO:0000259|Pfam:PF01555};
GN ORFNames=BN734_01960 {ECO:0000313|EMBL:CCZ26283.1};
OS [Ruminococcus] torques CAG:61.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Mediterraneibacter.
OX NCBI_TaxID=1263108 {ECO:0000313|EMBL:CCZ26283.1, ECO:0000313|Proteomes:UP000017998};
RN [1] {ECO:0000313|EMBL:CCZ26283.1, ECO:0000313|Proteomes:UP000017998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:61 {ECO:0000313|Proteomes:UP000017998};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ26283.1}.
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DR EMBL; CAZS010000099; CCZ26283.1; -; Genomic_DNA.
DR RefSeq; WP_022003293.1; NZ_HF995187.1.
DR AlphaFoldDB; R5QCG2; -.
DR Proteomes; UP000017998; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PIRSF; PIRSF015855; TypeIII_Mtase_mKpnI; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000017998};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 119..447
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 629 AA; 72494 MW; F8C854AF73ABCECA CRC64;
MEKMRFESVD GFQENIRRLA DIFPSCVKEQ KDNDGKTIRK VDINTLQLLL GINQKESETC
EFSWVGKREA VKEVYKPIRK TLRPVVQDSV EWDSTGNLYI EGDNLDVLKL LQESYLDSVK
VIYIDPPYNT GNDFIYADDF RIRAREYVNA GGASQDDKNR MYQNLDYSGR YHSDWCSMIY
ARLLAARNLL CDDGVIFISI DDNEQANLKK ICDEVFGERN FVNCFIWNCS TAGGIRPKFA
SKTHEYILCY AKNKTCLDMF FAPLSGEAIK MYREKDERGL YRDKDFVFKN KSTNANQKYE
IICPDGERVR PKDGYIYRFV RERFEQAKEE GLVTFKRTKT GPLVDQNGDQ AHWNIYIKKY
LGDAMGAPST LIPKEAVSIY NAGTQCVQEL FDGKRVFENV KPVNVIQYFI NMAAKDGDIV
MDFFSGSATT AHAVMQTEAD KNIDLHYILV QIPQECDKKS EAYKAGYKTI CEIGKERIRR
AAEKIKRENG CENRDFGFRV LRLDESNMED VYYMPEEYTQ EMLYGLETNI KPDRTDLDLL
FACLTEWGLL LSKPYSSEKI SGYTVHYYDG KELAACFNEN ISETVIRKIA GQHPRRAVFC
DASFSDSAAK INMSELFRTI SPETQIKVI
//
