ID   R5QFM2_9FIRM            Unreviewed;       724 AA.
AC   R5QFM2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:CCZ21036.1};
GN   ORFNames=BN766_00452 {ECO:0000313|EMBL:CCZ21036.1};
OS   Candidatus Apopatosoma intestinale.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Apopatosoma.
OX   NCBI_TaxID=1262966 {ECO:0000313|EMBL:CCZ21036.1, ECO:0000313|Proteomes:UP000018243};
RN   [1] {ECO:0000313|EMBL:CCZ21036.1, ECO:0000313|Proteomes:UP000018243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:724 {ECO:0000313|Proteomes:UP000018243};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ21036.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAZP010000188; CCZ21036.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5QFM2; -.
DR   STRING; 1262966.BN766_00452; -.
DR   Proteomes; UP000018243; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000018243}.
FT   DOMAIN          1..94
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
SQ   SEQUENCE   724 AA;  82624 MW;  335B9D693E328BC9 CRC64;
     MKVIKRNGAE MQFDIEKIVA AITKANEASE QDVRLTPMQI RRIAEAVELN CIRMNRAPGV
     EEIQDLVEKQ IMAHGAYEVA KKYITYRYTR NLIRRSNTTD DRILSLIECH NEEAKQENAN
     KNPTVNSVQR DYMAGEVSRD ITNRILLPED IVKAHEEGII HFHDTDYYAQ HMHNCDLVNL
     EDMLQNGTVI SGTMIERPHS FSTACNIATQ IIAQVASNQY GGQSISLTHL APFVQVSREK
     IRKTLREELD TLGTSVSDEK FAEVVESRLR EEIRRGVQTI QYQVVTLLTT NGQAPFVTVF
     MYLGEAKDER EKKDLAIIIE ETLLQRYQGV KNESGVYVTP AFPKLVYVLE EQNIHEDSPY
     YYLTELSAKC TARRMVPDYI SEKKMLELKV DKNGEGHCYT CMGCRSFLTP YIDENGKPKY
     YGRFNQGVVT INLVDVALSS GKDITKFWEI FDERLELCHR ALVCRHERLK GTLSDAAPIL
     WQYGALARLK KGEPIDKLLF GGYSTISLGY AGLYECVKYM TGKSHTDPVA TPFALDVMRH
     MNDACKKWKA EHNIDFSLYG TPLESTTYKF AKCLQKRFGI VPGITDKGYI TNSYHIHVTE
     QIDAFSKLAF EAQFQALSPG GAISYVEVPN MQQNIEAVLQ VMKFIYDNIM YAELNTKSDY
     CQECGYDGEI QIVEEDGKLI WKCPKCGNTD QSKMNVARRT CGYIGTQYWN QGRTQEIKER
     VLHL
//