ID R5QXQ1_9FIRM Unreviewed; 368 AA.
AC R5QXQ1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Transcriptional regulator GntR family with LacI sensor {ECO:0000313|EMBL:CCZ33735.1};
GN ORFNames=BN747_02213 {ECO:0000313|EMBL:CCZ33735.1};
OS Firmicutes bacterium CAG:646.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262995 {ECO:0000313|EMBL:CCZ33735.1, ECO:0000313|Proteomes:UP000018386};
RN [1] {ECO:0000313|EMBL:CCZ33735.1, ECO:0000313|Proteomes:UP000018386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:646 {ECO:0000313|Proteomes:UP000018386};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ33735.1}.
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DR EMBL; CAZW010000080; CCZ33735.1; -; Genomic_DNA.
DR AlphaFoldDB; R5QXQ1; -.
DR STRING; 1262995.BN747_02213; -.
DR Proteomes; UP000018386; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF95; RIBOSE OPERON REPRESSOR; 1.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000018386};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..73
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 368 AA; 42057 MW; 203FF634CA858175 CRC64;
MAKDSFLYEK VYRDLKEKIS QGILKEGDKL DAEEDMVKQY QVSAITIKKA LALLVQERLV
ERVRGRGSFV TGSAGKEAEE PVQETVSEPI QEEKLIGVIF EHISSSYGLQ LLYEMDHQVR
KAGYHLYPCF SYGNQELEKQ SITYLREIGA QGICIMPVHG SHYNTEILKM VIDGFPAVLI
DKKMEGIPLD SVRTDGEEAI RKLVGYLAKQ GKKNIAMITV EEKGTSSLME RKNGFFRGME
ECGQEAMPPC LLPYVDYEDP FQVYGKIYRE RIEEYIENYG AQLDGLVCLE YGLAMETEKI
LSEKGLLQKI RVCSVDENYL GPDQYHMTHV KQDEKRIAEC AVELLLKKIR TGERCWEDYL
IPGIFVEK
//
