ID R5RCM9_9PROT Unreviewed; 452 AA.
AC R5RCM9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Similar to UDP-N-acetylmuramate:L-alanine ligase MurC {ECO:0000313|EMBL:CCZ30597.1};
GN ORFNames=BN682_00555 {ECO:0000313|EMBL:CCZ30597.1};
OS Proteobacteria bacterium CAG:495.
OC Bacteria; Pseudomonadota.
OX NCBI_TaxID=1262987 {ECO:0000313|EMBL:CCZ30597.1, ECO:0000313|Proteomes:UP000018309};
RN [1] {ECO:0000313|EMBL:CCZ30597.1, ECO:0000313|Proteomes:UP000018309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:495 {ECO:0000313|Proteomes:UP000018309};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ30597.1}.
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DR EMBL; CAZU010000064; CCZ30597.1; -; Genomic_DNA.
DR AlphaFoldDB; R5RCM9; -.
DR STRING; 1262987.BN682_00555; -.
DR Proteomes; UP000018309; Unassembled WGS sequence.
DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR InterPro; IPR000713; Mur_ligase_N.
DR PANTHER; PTHR43445:SF3; UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE; 1.
DR PANTHER; PTHR43445; UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE-RELATED; 1.
DR Pfam; PF01225; Mur_ligase; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF51984; MurCD N-terminal domain; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CCZ30597.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Reference proteome {ECO:0000313|Proteomes:UP000018309}.
FT DOMAIN 4..105
FT /note="Mur ligase N-terminal catalytic"
FT /evidence="ECO:0000259|Pfam:PF01225"
FT DOMAIN 112..283
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
FT DOMAIN 304..383
FT /note="Mur ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02875"
SQ SEQUENCE 452 AA; 49484 MW; 460DA0D91D9B47B9 CRC64;
MKKIAFCAAA GNGISPLEQI MIKKGYEVYG SDSSFDEGLN QDRKAALESV GLKIVPQDGS
AVFPDTECLY ISSIINEENP DIKAARKYNV PVKKRSDLLE EIFSGYAKGI AVGGTAGKTT
TTAMIGYILD RLGQKPCMIN GGMLCNYEDR PGLPNYLYNE SDVCVIEADE SDGSIQKYHP
YIGIVNNISH DHTSMEKLVE YFTNFASHVQ YALIVNYDCP LTRSLTSPKK TFSFSIKDSH
ADIFAYNIKA VEHGVEYSID GKKFSLALLG KFNVANALAA ISACMMLGID KFDAAKALEG
FTGVKVRLEK VGSAKGITFY ADFAHNPTKI AASAAAIKEH PGRLIMMYQP HTPFSVMNTG
AEVAAELSKV ISAEDIVLMQ EIYELTPKDS VSSNDIITKI KAAGHQNAFF MPRREETRKF
ILANAKPGDR VVIMGAHDNS LPDFSRQLCK EI
//
