ID   R5TX68_9BACE            Unreviewed;       502 AA.
AC   R5TX68;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Glycoside hydrolase family 30 candidate beta-glycosidase {ECO:0000313|EMBL:CCZ70355.1};
GN   ORFNames=BN759_02497 {ECO:0000313|EMBL:CCZ70355.1};
OS   Bacteroides sp. CAG:702.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262747 {ECO:0000313|EMBL:CCZ70355.1, ECO:0000313|Proteomes:UP000017962};
RN   [1] {ECO:0000313|EMBL:CCZ70355.1, ECO:0000313|Proteomes:UP000017962}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:702 {ECO:0000313|Proteomes:UP000017962};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ70355.1}.
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DR   EMBL; CBAM010000150; CCZ70355.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5TX68; -.
DR   STRING; 1262747.BN759_02497; -.
DR   Proteomes; UP000017962; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 2.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361188, ECO:0000313|EMBL:CCZ70355.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017962};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..502
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004405199"
FT   DOMAIN          66..176
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          232..435
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          438..499
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   502 AA;  58176 MW;  71FCEDF10F5B8B02 CRC64;
     MKPIFLKWTF AVCFLSMVYG IQAQSYVWIC STENNYWKED ETKLQSRPVQ TPLLEIDGTE
     KGVPFKAWGT TFNELDWDAL LALTRDEQDE IMHNLFAPDG DLKFTRGRIP MNASDYARSW
     YSCDEVAGDL ELRYFNIDRD KLGIIPLIRT AQKFNPRLTF WTSPWSPPSW MKINGDYPVL
     SSRFNRQDKR LDYLLYGSQD GVDEDEMKFL GEREGQFPRK LATQDYFIQD PRYLQAYANY
     FCKFIDAYKA QGVNIDMVIY QNEAYSYTPY PGCAWTAEGT IRFNRDYLAP ALKKHHPDVK
     LYLGTFNTNR QDHVEKVLSD DRLRACIEGL AFQWEGRQIL PAIRRQYPGF HYICSESECG
     NGAMDWKAGE HTFFLISDNV GNGCDEWFNW NFLLPKHGTS PWGWNQNALI ELDSETRTFR
     YTAEYYAVKH FSHFVVPGSE MIGYAPKEKD GTIAVVYRTP EKKIVVIAGN LGDTPQPVSV
     KIGKKYLNVT LDAHSLHTFV MK
//