ID   R5UGD0_9BACE            Unreviewed;       686 AA.
AC   R5UGD0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Peptidase family M3 {ECO:0000313|EMBL:CCZ74744.1};
GN   ORFNames=BN535_00075 {ECO:0000313|EMBL:CCZ74744.1};
OS   Bacteroides caccae CAG:21.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1263037 {ECO:0000313|EMBL:CCZ74744.1, ECO:0000313|Proteomes:UP000017990};
RN   [1] {ECO:0000313|EMBL:CCZ74744.1, ECO:0000313|Proteomes:UP000017990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:21 {ECO:0000313|Proteomes:UP000017990};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU003435};
CC       Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC   -!- SIMILARITY: Belongs to the peptidase M3 family.
CC       {ECO:0000256|ARBA:ARBA00006040, ECO:0000256|RuleBase:RU003435}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCZ74744.1}.
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DR   EMBL; CBAN010000189; CCZ74744.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5UGD0; -.
DR   Proteomes; UP000017990; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd06456; M3A_DCP; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   Gene3D; 1.10.1370.10; Neurolysin, domain 3; 1.
DR   InterPro; IPR034005; M3A_DCP.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR024077; Neurolysin/TOP_dom2.
DR   InterPro; IPR024080; Neurolysin/TOP_N.
DR   InterPro; IPR045090; Pept_M3A_M3B.
DR   InterPro; IPR001567; Pept_M3A_M3B_dom.
DR   PANTHER; PTHR43660; DIPEPTIDYL CARBOXYPEPTIDASE; 1.
DR   PANTHER; PTHR43660:SF1; DIPEPTIDYL CARBOXYPEPTIDASE; 1.
DR   Pfam; PF01432; Peptidase_M3; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU003435};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU003435};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT   DOMAIN          232..682
FT                   /note="Peptidase M3A/M3B catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01432"
SQ   SEQUENCE   686 AA;  79345 MW;  0B526EC9AA06C9B3 CRC64;
     MNNITNAQNP FFGQYQTPHA TVPFDRIKTE HYEPAILEGI KQQNAEIDAI ILNPEKANFN
     NTIEAFEESG ELLDRVVSVF GNMLSAETND NLQELAQKIM PLLSEHSNNI TLNEKLFARV
     KEVYDQKETL QLTQEQSQLL ENAYNSFVRH GANLEGEARE EYRKLTTELS KLTLDFSENN
     LKETNSYQML LTKKESLAGL PEIIVEAAAE TAKSEGKKGW AFTLHAPSYV PFMTYADNRD
     LRHRLYMAYN TKCTHDNEFN NIDIVKKIAN TRMKIAQLLG YKDYAEYTLK RRMAENSRAV
     YKLLNQLLEA YTPTAEAEYK DVQELARLEQ GNDFILMPWD WSYYSNKLKD KKFNINEEML
     RPYFELEQVK KGVFGLAEKL YGITFRKNTE IPVYHKEVEA YEVFDKDGQF LAILYTDFHP
     RLGKRAGAWM TSYKEQWIDK KTGENSRPHI SVVMNFTKPT ENKPALLTFN EVETFLHEFG
     HSLHGMFANS TYKSLSGTNV YWDFVELPSQ IMENFAIEKD FLNTFARHYQ TGEVLPDELI
     QRLVDASNFN VAYACLRQIS FGLLDMAWYT RNVPFEGDVK VYEQEAWKKA QILPVVKETC
     MSTQFSHIFA GGYSAGYYSY KWAEVLDADA FSLFKQKGIF NQDVAESFRN NILSKGGTEH
     PMVLYKRFRG QEPTIDALLI RNGIKN
//