ID R5UIB3_9BACT Unreviewed; 547 AA.
AC R5UIB3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=BN754_01059 {ECO:0000313|EMBL:CCZ75454.1};
OS Alistipes finegoldii CAG:68.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1263035 {ECO:0000313|EMBL:CCZ75454.1, ECO:0000313|Proteomes:UP000018154};
RN [1] {ECO:0000313|EMBL:CCZ75454.1, ECO:0000313|Proteomes:UP000018154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:68 {ECO:0000313|Proteomes:UP000018154};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ75454.1}.
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DR EMBL; CBAO010000034; CCZ75454.1; -; Genomic_DNA.
DR RefSeq; WP_014776145.1; NZ_HF997559.1.
DR AlphaFoldDB; R5UIB3; -.
DR Proteomes; UP000018154; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 30..160
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 166..513
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 345
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 547 AA; 61765 MW; 2BDF587E45D9AA5F CRC64;
MKRLLPVLAL FAVLCGCCSC GRVIPTDGEV AVVPLPEHIV EGQGTFRLTS DAEVVLLFDD
ERLSGVTAAL NKVLMPLFGR GPRVRHADKA ADHAVNVTRD ETMPAEAYRL FVTPCRIDIV
AGGAQGAFYA VQTLRQLLPA AAYEADDVRA VELPVVTIED KPCLGYRGMM LDVGRHFFTV
DEVKEALDIM ALHKLNVFHW HLTDDQGWRI EIRKYPKLTE IGSVRSRTLI GRDPGGTYDE
NCKFDETPYG GYYTQDEIRD VVNYAAERFI TVIPEIEFPG HAVGALASYP WLGCTGEQYE
VRQTWDIDDR VFCIGKETTF EFIEGVLEEV LELFPSEYIH IGGDECPTVM WKKCPHCKAR
MKAERLKRPR RLQNYATARV EKFLNAHGRR LIGWDEILEG EVTPTATIMS WRGAEGGIKA
AKMGNHAIMA PTTHCYLDYY QTRDTAGEPL AIGGYLPVEK VYSLDPYEML TADEQRCILG
VQANLWTEYI ATWPHAEYML LPRLSALAEV GWSLDRKDYG DYLRRVRRLA KIYDACGYNY
AKHIFGK
//
