ID R5UVI4_9BACE Unreviewed; 672 AA.
AC R5UVI4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=BN535_01326 {ECO:0000313|EMBL:CCZ75116.1};
OS Bacteroides caccae CAG:21.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1263037 {ECO:0000313|EMBL:CCZ75116.1, ECO:0000313|Proteomes:UP000017990};
RN [1] {ECO:0000313|EMBL:CCZ75116.1, ECO:0000313|Proteomes:UP000017990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:21 {ECO:0000313|Proteomes:UP000017990};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ75116.1}.
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DR EMBL; CBAN010000206; CCZ75116.1; -; Genomic_DNA.
DR AlphaFoldDB; R5UVI4; -.
DR Proteomes; UP000017990; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 26..143
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 146..249
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 285
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 672 AA; 77629 MW; 3F00E29BD7159902 CRC64;
MKNRLILFIY IIINLCTISV VKAGDYHLLP QPQKFTPSHL NFQVNKVQLS TPVLQQEWET
LISEMGGTVS PKATGTIEVK LLPTLPEIPM NQDEAYRLSI TKKRIIVEAV TERGVYWAMQ
TLRQLAEKRN SKTHIQGAEI IDWPAFRVRG FMQDVGRSYI SLDELKREIA ALAKFKINVF
HWHLTENQSW RLESKIFPML NDSANTTRMP GKYYTLEEAK ELVAFCKAHH MTLIPEIDMP
GHSAAFIRTF RHDMQSPEGM KILKLLMDEV CDTFDVPYLH IGTDEVQFTN PRFVPEMVSY
VRSKGKKVIS WNPGWRYKPG EIDMTQLWSY RGKAQKGIPA IDSRFHYLNH FDTFGDIIAL
YNSRIYNKEQ GSEDLAGTIL AIWNDRLVST EWGMIIENNF YPNMLAMAER AWKGGGTEYF
DKNGTILPTD EHSELFRSFA DFERRLLWHK EHTFDGYPFA YVRQTNVKWN ITDAFPNEGN
LAKAFPPEET LQDSYSYGGK TYNVRPAIGA GIYLRHVWGT LIPGFYKEPK ENHTAYAYTY
VYSPKEQNVG LWAEFQNYGR SEADLPPLPG KWDYKESRIW INEQEILPPV WTATHRTKSN
EIALGNENCV ARPPLEVHLQ KGWNKVLLKL PVGKFVSPEV RLVKWMFTTV FVTLDGQKAV
EGLIYSPNKT LE
//
