ID R5V3Y2_9FIRM Unreviewed; 511 AA.
AC R5V3Y2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=PLD phosphodiesterase domain-containing protein {ECO:0000259|PROSITE:PS50035};
GN ORFNames=BN742_00345 {ECO:0000313|EMBL:CCZ85283.1};
OS Firmicutes bacterium CAG:631.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262996 {ECO:0000313|EMBL:CCZ85283.1, ECO:0000313|Proteomes:UP000018035};
RN [1] {ECO:0000313|EMBL:CCZ85283.1, ECO:0000313|Proteomes:UP000018035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:631 {ECO:0000313|Proteomes:UP000018035};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ85283.1}.
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DR EMBL; CBAS010000047; CCZ85283.1; -; Genomic_DNA.
DR AlphaFoldDB; R5V3Y2; -.
DR STRING; 1262996.BN742_00345; -.
DR Proteomes; UP000018035; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09110; PLDc_CLS_1; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR027379; CLS_N.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR Pfam; PF13396; PLDc_N; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000018035};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 245..272
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 424..451
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 511 AA; 59857 MW; C0D0B2E6DC423B5F CRC64;
MKHILRIILY LFNVFIKIII FFVSLALQIY VLWLSIYSVP HYYPLYIATV AISIIPITYV
FNSSNNSSYK MSWIILILVL PIVGMIMYLF FGQGRSFSKK RALKLKEYVT PYVQKNDTLL
YIRHNTDKKI ANLLHATSKL PFYIDDQVTF LNDGAIWFEK MMEDIQKAKK YVFLEYFIFS
DGETLERLSS LLIQKAQEGV QIKIILDDIG SKKGLKQKTI DRLKEHPNLK VYSFNPMGMF
FSLNLNFRNH RKMTIIDGKI AYCGGTNIAD EYVHKKDRFG FWRDNACRYA GSAVNSFVFT
FCIDWFMSAK EKLNMEEYFY DHPQIPSSKE SYICPFSDGP GDDDNPGYTL FQSMIENAKY
SIYISTPYFI IDREFIGSLE NAAKSGIDVR LLIPHIPDKK IPYIMTYYHV GRLIKSGVKV
YRYTPGFTHA KNIIIDDKYT FNGTFNLDYR SLFLHFECGA FHINKDLAKE MKDDFHQALK
QSRQVSYQEW KKRPVYYRII EFLGSLFAPL L
//
