ID R5W563_9BACT Unreviewed; 319 AA.
AC R5W563;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Alanine racemase {ECO:0000313|EMBL:CCZ98363.1};
GN ORFNames=BN505_01340 {ECO:0000313|EMBL:CCZ98363.1};
OS Alistipes sp. CAG:157.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1262692 {ECO:0000313|EMBL:CCZ98363.1, ECO:0000313|Proteomes:UP000018346};
RN [1] {ECO:0000313|EMBL:CCZ98363.1, ECO:0000313|Proteomes:UP000018346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:157 {ECO:0000313|Proteomes:UP000018346};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCZ98363.1}.
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DR EMBL; CBAZ010000048; CCZ98363.1; -; Genomic_DNA.
DR AlphaFoldDB; R5W563; -.
DR Proteomes; UP000018346; Unassembled WGS sequence.
DR GO; GO:0008784; F:alanine racemase activity; IEA:InterPro.
DR GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR CDD; cd00430; PLPDE_III_AR; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR000821; Ala_racemase.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR011079; Ala_racemase_C.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR029066; PLP-binding_barrel.
DR NCBIfam; TIGR00492; alr; 1.
DR PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR Pfam; PF00842; Ala_racemase_C; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PRINTS; PR00992; ALARACEMASE.
DR SMART; SM01005; Ala_racemase_C; 1.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000018346}.
FT DOMAIN 191..317
FT /note="Alanine racemase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01005"
FT BINDING 85
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT BINDING 261
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
SQ SEQUENCE 319 AA; 35081 MW; 30579A9BF6C51A24 CRC64;
MLDKQGVNYL AVAFADEGVT LREKGIAMPI VVLNADSDSF ALMVANRLEP EIYNFRSLER
FIAAVRDAGE TSWPVHIKID TGMHRLGFRM EDMPELAAFL RREAGAVAAR SVFSHLAAAD
MPEEDGFTRS QIDYFRRTVQ ALADGLGYRP LMHILNTAGM ERFPEARFDM CRLGIGLYGV
SCTEGEALRP VSRLLTRIVQ VKELAQSETV GYGRSGKLAR DSRLATIPIG YADGLDRRLG
CGNWSVLVNG RPAPIVGRIC MDSCMVDVTG MNVSEGDEVT VFGSTPGNTV SDMAVLLGTI
PYEIMTSVSE RVKRIYLKE
//
