ID   R5XZ80_9FIRM            Unreviewed;       416 AA.
AC   R5XZ80;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Putative capsule biosynthesis protein {ECO:0000313|EMBL:CDA19895.1};
GN   ORFNames=BN680_00909 {ECO:0000313|EMBL:CDA19895.1};
OS   Ruminococcus sp. CAG:488.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262959 {ECO:0000313|EMBL:CDA19895.1, ECO:0000313|Proteomes:UP000018248};
RN   [1] {ECO:0000313|EMBL:CDA19895.1, ECO:0000313|Proteomes:UP000018248}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:488 {ECO:0000313|Proteomes:UP000018248};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CapA family.
CC       {ECO:0000256|ARBA:ARBA00005662}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA19895.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBBI010000082; CDA19895.1; -; Genomic_DNA.
DR   AlphaFoldDB; R5XZ80; -.
DR   STRING; 1262959.BN680_00909; -.
DR   Proteomes; UP000018248; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR019079; Capsule_synth_CapA.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR33393:SF12; LIPOPROTEIN-RELATED; 1.
DR   PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   Pfam; PF09587; PGA_cap; 1.
DR   SMART; SM00854; PGA_cap; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          67..325
FT                   /note="Capsule synthesis protein CapA"
FT                   /evidence="ECO:0000259|SMART:SM00854"
SQ   SEQUENCE   416 AA;  45608 MW;  43D33C86CAB93AB5 CRC64;
     MKDNLKWTKS RVFLISINCI LSVAIVVSAM MIVIDKSRIK NGAVFTGGEK ETTASDSSVS
     GTAGSARLMI AGDNVVYKTV YTQANQKAGG SGYDFSSAYD GIKEIIAKSD IAMVSQNTVM
     DDKNEPSASP EFNTPDQMLD KLLDLGFDVF NQANDHIMDM GLSGAINDIA LFKAKENQAL
     LTGLYENKEE MMKPQVKEVN GIKISFVGIT QSLGDYELSE ETDIGILNLS DSRSTSDELE
     GTMKQLVESA KNASDIVCVT VHWDGESTSE LSDTQKDIIS KLLKYGVDII VGTGKNDLQK
     FEYRSNGDGE QALVIPSLGK VISLEESVDS FLGGIADITV SKDPKTNKTH VSSAKLIPTV
     TVYEEDYANV RVLPFAKCTE DIIKKHGFVL EDETFTYSYI KNYYNQKFSD TLELNY
//