ID R5Z373_9FIRM Unreviewed; 625 AA.
AC R5Z373;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Predicted nucleoside-diphosphate sugar epimerases {ECO:0000313|EMBL:CDA34183.1};
GN ORFNames=BN700_00631 {ECO:0000313|EMBL:CDA34183.1};
OS Firmicutes bacterium CAG:536.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263028 {ECO:0000313|EMBL:CDA34183.1, ECO:0000313|Proteomes:UP000018332};
RN [1] {ECO:0000313|EMBL:CDA34183.1, ECO:0000313|Proteomes:UP000018332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:536 {ECO:0000313|Proteomes:UP000018332};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA34183.1}.
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DR EMBL; CBBQ010000050; CDA34183.1; -; Genomic_DNA.
DR AlphaFoldDB; R5Z373; -.
DR Proteomes; UP000018332; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018332};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 296..578
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 625 AA; 71077 MW; DC8658C318E7BDE4 CRC64;
MQLNKSELGK DSSYRKRLLL IVLADIVCIA FSYLFALWVR FDFVLSNIEA KYLINLTWFI
PVIVLISIFV YYFMRLYHSI WIFASVNELI SIIEAYLILL VAVVLCSFIP RFNLPRSVFL
MGYFFSGVSC VAIRFMYRFL RYINLDNSKE TCGERVLLVG AGSSAREVIR ASRSNPNHDF
EVEALVDDNP DKYKRYLEGI QIEGNRHTIP ELVKKHHINK IILAMPGASA QDKKAIINIC
KETNCKVQTV PSMAQIVNED FKVSKIRDVE IEELLGREET HINLEEIYKS LENRVVMVTG
GGGSIGSELC RQIARAKPKQ LIIFDIYENN AYSIQQELKR KVPDLNLVTL IGSVRNTKRV
DSVLDKYRPE IIFHAAAHKH VPLMEDSPNE SIKNNVMGTY KVAQAAARYG VKRFLLISTD
KAVNPTNIMG ASKRLCEMVI QMMSRKHPET IYMAVRFGNV LGSNGSVIPL FKKQIAEGGP
VTVTDPNIIR YFMTIPEAVS LVLEASLYAK GGEIFVLDMG EPVKIDDMAR NLIKLSGLTP
DVDIKVEYTG LRPGEKLYEE LLMDEEGMTK TENKLIFIGH PIKMDDQQFE KDLAYIDEAS
YQEVNDIKEI VQKIVPTYHP DLETK
//
