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Database: UniProt
Entry: R6ARC2_9CLOT
LinkDB: R6ARC2_9CLOT
Original site: R6ARC2_9CLOT 
ID   R6ARC2_9CLOT            Unreviewed;       429 AA.
AC   R6ARC2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=BN491_00487 {ECO:0000313|EMBL:CDA51284.1};
OS   Clostridium sp. CAG:138.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262775 {ECO:0000313|EMBL:CDA51284.1, ECO:0000313|Proteomes:UP000017905};
RN   [1] {ECO:0000313|EMBL:CDA51284.1, ECO:0000313|Proteomes:UP000017905}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:138 {ECO:0000313|Proteomes:UP000017905};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA51284.1}.
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DR   EMBL; CBBZ010000039; CDA51284.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6ARC2; -.
DR   STRING; 1262775.BN491_00487; -.
DR   Proteomes; UP000017905; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 2.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 2.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 2.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017905}.
FT   DOMAIN          289..427
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   429 AA;  49994 MW;  924D3DF2AF66CB20 CRC64;
     MSTELYFYQR QNGKEYAMKQ SRLDRLNPDK TPKHLRKKMS EQEFFNDYLE GKKQNARLYG
     EYVEYAENLA SKGMAAIIDA IDSSFYPEQF LSRFSDIENE GVRPSAVLIY NICHIPPSEQ
     VSRFSHLLSR KPACIIGDYH SSFIPDDVAI FIMEDSTGDY SLAKEIIQNT DVLGHSKCYV
     FVSHSHKDIA KVRKVRNLLE NHNFEPILFY LRCMDNGNED TEKLRDLIHK EIDSREWFLY
     LESANSKSSD WVQDEIEYIK KRENHVIKKI CIDSLSEDDL NSSVFDLIDK LSVFISYSHS
     DVEIAKVFYD EFCNYGLSVF FDQNELKVGQ SWSDQIEKGI NDASEKGRVV LLLTKDSLHS
     HWIRYELEKA IASNGRIYPI CLDEDSNIDT DLFPDSLKSI RFIRCQPNTE SIHTCVFEIV
     KDIRSRYQL
//
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