ID R6CHD0_9FIRM Unreviewed; 513 AA.
AC R6CHD0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Polar amino acid transport system substrate-binding protein {ECO:0000313|EMBL:CDA72274.1};
GN ORFNames=BN718_01123 {ECO:0000313|EMBL:CDA72274.1};
OS Ruminococcus sp. CAG:579.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262963 {ECO:0000313|EMBL:CDA72274.1, ECO:0000313|Proteomes:UP000018387};
RN [1] {ECO:0000313|EMBL:CDA72274.1, ECO:0000313|Proteomes:UP000018387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:579 {ECO:0000313|Proteomes:UP000018387};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 3 family.
CC {ECO:0000256|ARBA:ARBA00010333}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA72274.1}.
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DR EMBL; CBCK010000059; CDA72274.1; -; Genomic_DNA.
DR AlphaFoldDB; R6CHD0; -.
DR STRING; 1262963.BN718_01123; -.
DR Proteomes; UP000018387; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR CDD; cd00996; PBP2_AatB_like; 1.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR InterPro; IPR043429; ArtM/GltK/GlnP/TcyL/YhdX-like.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR018313; SBP_3_CS.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR01726; HEQRo_perm_3TM; 1.
DR PANTHER; PTHR30614:SF0; L-CYSTINE TRANSPORT SYSTEM PERMEASE PROTEIN TCYL; 1.
DR PANTHER; PTHR30614; MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
DR PROSITE; PS01039; SBP_BACTERIAL_3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000018387};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..513
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039594365"
FT TRANSMEM 311..333
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 345..372
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 384..403
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 481..502
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 307..502
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 513 AA; 56772 MW; D92A65F788020016 CRC64;
MILKKLISFA AAAVMTAAAV YISPAELTMS ASANTLEDKE FIVGFDAEFP PYGYKDDNGE
YVGFDLDLAQ EVCDRNGWTL KKQPIEWNSK DMELKNGTID CLWNGFTMNG RESKYTWSVP
YVDNSQVVIV KDNSGINELD DLAGKIVAVQ ADSSALAALT GEDATEENLA LAESFKDLQQ
VGDYNSAFMN LDSGAVDAIA MDIGVASYEM NSRGGGFKML DDHLSAEEYG VGFLLGNTEL
RDAVQNTLFD MLDDGTFEKI AKDWGLEESV CLSRDEVTEN GNVSDSAVAK DKKPGFGEKF
ANISSQLLRG LLASALIFVL TIILSMPLGL LVMAGRMSKF APLRWLIKLY ISIARGTPLM
LQLLVVFFGP YYLFNVHTPP NYRFAAVIIG FTLNYAAYFA EIYRSGIQAV PRGQYEAAEV
LGYTRMQTNV KIIFPQMIKN IIPSVTNEVI TLVKDTSLAF AVSFTEMFTL AKQIAAAQTT
IMPLFIAGVF YYIFNFVVAF VMERIEKKLN YYR
//
