ID   R6CU09_9CLOT            Unreviewed;       437 AA.
AC   R6CU09;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Membrane insertion protein {ECO:0000313|EMBL:CDA68807.1};
GN   ORFNames=BN687_00788 {ECO:0000313|EMBL:CDA68807.1};
OS   Clostridium sp. CAG:510.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262816 {ECO:0000313|EMBL:CDA68807.1, ECO:0000313|Proteomes:UP000018120};
RN   [1] {ECO:0000313|EMBL:CDA68807.1, ECO:0000313|Proteomes:UP000018120}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:510 {ECO:0000313|Proteomes:UP000018120};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC       {ECO:0000256|RuleBase:RU003945}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA68807.1}.
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DR   EMBL; CBCI010000075; CDA68807.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6CU09; -.
DR   STRING; 1262816.BN687_00788; -.
DR   Proteomes; UP000018120; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd20070; 5TM_YidC_Alb3; 1.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR028055; YidC/Oxa/ALB_C.
DR   InterPro; IPR047196; YidC_ALB_C.
DR   NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR   PANTHER; PTHR12428:SF65; INNER MEMBRANE PROTEIN ALBINO3, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR12428; OXA1; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018120};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003945};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        250..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          42..338
FT                   /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02096"
FT   REGION          380..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        380..398
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   437 AA;  47700 MW;  FDCD08859157A573 CRC64;
     MTSIVLTSCG NLPIIKQVAW LLGQVMNALF NVLDLIGIPN IGLAIFLFTI IVYLLMMPLT
     IKQQKFSKLS AKMNPELQAI RNKYKNRTDT DSQMQMNAET QAVYAKYGVS PTGSCLQLFI
     QMPILFALYE VIYSIPSFVT KIGNAFSSVA GEIISSGKVS AFVESVKGAS TYITNVDNVT
     ESTLINALNR VNYSDVEVFI NNNFAGNAAV AEGMSQIERY NSFLVKGFSL ANSPSSVVTS
     FFNSGNAGKI TVAMLIIAIA IPVLSAVTQW VNVMLMPKQE TGNGNGDMTD TMASSMKTMN
     MIMPIMSAFF CYTLPAGLGL YWISGSLVRS VQQVVINKHI DKMDLDEVIA KNADKSAKKM
     EKLEKNQAKL QQYANMNTKN MGGTVSTKSY TAKTTDTKNA NTDNKEVKKT SSTGAKPGSL
     MAKANLVKDY NERNNKN
//