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Database: UniProt
Entry: R6E4W6_9FIRM
LinkDB: R6E4W6_9FIRM
Original site: R6E4W6_9FIRM 
ID   R6E4W6_9FIRM            Unreviewed;       258 AA.
AC   R6E4W6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=N-Dimethylarginine dimethylaminohydrolase {ECO:0000313|EMBL:CDA92299.1};
GN   ORFNames=BN553_00630 {ECO:0000313|EMBL:CDA92299.1};
OS   Firmicutes bacterium CAG:238.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263011 {ECO:0000313|EMBL:CDA92299.1, ECO:0000313|Proteomes:UP000018260};
RN   [1] {ECO:0000313|EMBL:CDA92299.1, ECO:0000313|Proteomes:UP000018260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:238 {ECO:0000313|Proteomes:UP000018260};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DDAH family.
CC       {ECO:0000256|ARBA:ARBA00008532}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA92299.1}.
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DR   EMBL; CBCS010000207; CDA92299.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6E4W6; -.
DR   Proteomes; UP000018260; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR033199; DDAH-like.
DR   PANTHER; PTHR12737:SF9; DIMETHYLARGININASE; 1.
DR   PANTHER; PTHR12737; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE; 1.
DR   Pfam; PF19420; DDAH_eukar; 1.
DR   SUPFAM; SSF55909; Pentein; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CDA92299.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018260}.
FT   ACT_SITE        166
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT   ACT_SITE        253
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
SQ   SEQUENCE   258 AA;  28974 MW;  6C362DD57F2DE65A CRC64;
     MKKFNHVIVR RPCRAMVDGI TSAPELGKPD YELALKEHDA YIEALKQCDV DVTVLEADER
     YPDSCFVEDP ALITRECAII TNPGAESRNG EKFEIVDAVR KFFPEDRIEY IKAPGTLEGG
     DVMMVGDHFY VGRSARTNEE GIRQLTEILA KYGMTCSEVK LEKVLHLKTG VNYLENNNML
     VSGEFVTKPD FEKYNKVEIP EEEAYAANCI WVNDTVIVPE GYPAVLAAVQ SLGYKTLLVD
     TSEYRKLDGG LSCLSLRF
//
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